Results 1 to 10 of about 2,827 (92)

Structural Evolution of TIR-Domain Signalosomes

Frontiers in Immunology, 2021
TIR (Toll/interleukin-1 receptor/resistance protein) domains are cytoplasmic domains widely found in animals and plants, where they are essential components of the innate immune system.
Surekha Nimma, Weixi Gu, Natsumi Maruta, Yan Li, Mengqi Pan, Forhad Karim Saikot, Bryan Y. J. Lim, Helen Ying McGuinness, Zannati Ferdous Zaoti, Sulin Li, Sneha Desa, Mohammad Kawsar Manik, Jeffrey D. Nanson, Bostjan Kobe   +13 more
doaj   +1 more source

Localization and Regulation of Two NAD Nucleosidases in Ehrlich Ascites Cells [PDF]

European Journal of Biochemistry, 1968
After differential centrifugation of Ehrlich ascites cells by the de Duve method, NAD nuclosidase activities were found in the nuclear and the microsomal fractions, but not in the lysosomal fraction. The nuclear NAD nucleosidase is inhibited 50% by 0.2 mM nicotinamide and is highly specific for β-NAD.
K W, Bock, V, Gäng, H P, Beer, R, Kronau, H, Grunicke   +4 more
openaire   +2 more sources

NAD(P) hydrolyzing enzymes in skipjack liver. II. Physico-chemical and enzymatic properties of NAD (P) nucleosidase.

NIPPON SUISAN GAKKAISHI, 1977
The physico-chomical and enzymatic properties of NAD (P) nucelsidase from skipjack liver was examined using a partially purified and two purified specimens (Frs. I and II). The molecular weights of Fr. I and II enzymes were estimated to be 30, 000 and 20, 000 and the isoelectric points to be 3.5 and 4.3, respectively. On SDS-electeophoresis, the Fr. II
ABE, Hiroki, SHIMIZU, Chiaki, MATSUURA, Fumio   +2 more
openaire   +3 more sources

Identification of co-expressed central genes and transcription factors in acute myocardial infarction and diabetic nephropathy

BMC Medical Genomics
Background Acute myocardial infarction (AMI) and diabetic nephropathy (DN) are common clinical co-morbidities, but they are challenging to manage and have poor prognoses.
Bo Li, Xu Zhao, Wanrun Xie, Zhenzhen Hong, Ye Cao, Yi Zhang, Yan Ding   +6 more
doaj   +1 more source

NAD(P) hydrolyzing enzymes in skipjack liver. I. Purification of NAD(P) nucleosidase.

NIPPON SUISAN GAKKAISHI, 1976
ABE, Hiroki, SHIMIZU, Chiaki, MATSUURA, Fumio   +2 more
openaire   +3 more sources

E2F5 Overexpression in Laryngeal Squamous Cell Carcinoma: Associations With Neutrophil Extracellular Traps in the Tumor Microenvironment. [PDF]

World J Oncol
Wu KJ, Zhao F, Li YF, Chen Y, Wen JY, Qin DY, He RQ, Xiao L, Li DM, Li B, Li Q, Li MJ, Chen G, Dang YW, Jiang JS.   +14 more
europepmc   +1 more source

Quantification of SARM1 NADase Activity in Human Peripheral Blood Mononuclear Cells. [PDF]

FASEB J
Dabill LF, Shen IR, Brazill JM, Neiner A, Sasaki Y, Scheller EL.   +5 more
europepmc   +1 more source

Targeting the sirtuin 6-NF-κB p65 axis by 6-hydroxyhyoscyamine hydrobromide: a deacetylation-driven new therapy for diabetic wounds. [PDF]

Cell Mol Biol Lett
Chen J, Qin S, Xing Z, Wan F, Yin J, Peng C, Li D.   +6 more
europepmc   +1 more source

NAD⁺ Enhancer Nicotinamide Riboside Alters Extracellular Purine Metabolism in Human Endothelial Cells. [PDF]

Int J Mol Sci
Harasim-Krawcewicz G, Mierzejewska P, Kawecka A, Frańczak MA, Król O, Presler M, Jędrzejewska A, Kutryb-Zając B, Smoleński RT, Słomińska E.   +9 more
europepmc   +1 more source

Transition-state analysis of the arginine-specific human ADP-ribosyltransferase 1. [PDF]

Proc Natl Acad Sci U S A
Groom DP, Aguilan JT, Lopacinski A, Garforth SJ, Schramm VL.   +4 more
europepmc   +1 more source