Results 31 to 40 of about 1,064,600 (267)
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53 independent pathways [PDF]
, 2014 Most cancer cells use aerobic glycolysis to fuel their growth. The enzyme lactate dehydrogenase-A (LDH-A) is key to cancer’s glycolytic phenotype, catalysing the regeneration of nicotinamide adenine dinucleotide (NAD þ ) from reduced nicotinamide adenine
Allison, Simon J. +6 more
core +1 more source
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction
Circulation Research, 2021 Supplemental Digital Content is available in the text. Rationale: Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies.
Dan Tong +13 more
semanticscholar +1 more source
Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]
, 1994 Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O +8 more
core +1 more source
Information and Material Support to Environmental Education in Slovakia in the Times of Crisis
Acta Educationis Generalis, 2023 Introduction: The undergoing globalization brings epidemiological, economical, energetical, and environmental security risks. The current task in the field of improving the quality of the environment is educating students in schools for adaptation to the
Bilčík Alexander +3 more
doaj +1 more source
Historical Agricultural Landforms—Central European Bio-Cultural Heritage Worthy of Attention
Land, 2022 Knowledge about past agricultural land management can bring solutions for future needs. One undervalued historical type of historical rural landscape in temperate Europe is termed plužiny.
Johana Zacharová +9 more
doaj +1 more source
The CD38 glycohydrolase and the NAD sink: implications for pathological conditions.
American Journal of Physiology - Cell Physiology, 2022 Nicotinamide adenine dinucleotide (NAD) acts as a cofactor in several oxidation-reduction reactions and is a substrate for a number of non-redox enzymes.
J. D. Zeidler +11 more
semanticscholar +1 more source
Arhitekture računala za adaptivno digitalno formiranje dijagrama usmjerenosti radarske antene
Vojnotehnički Glasnik, 1990 Kombiniranjem arhitekture sa slike 7 s principom računala upravljanog tokom podataka (data flow) (u literaturi je takva arhitektura poznata kao 'wavefront processor' ili polja valne fronte), dobivaju se dodatna poboljšanja i u smislu povećanja brzine i u
Karlo Nađ
doaj +1 more source
Applied Sciences, 2021 Second-generation biofuel crop miscanthus is one of the most promising plants tested for phytomanagement of contaminated sites. In this preliminary pot case study, the most used hybrid Miscanthus x giganteus was cultivated in three different real ...
Diana Nebeská +7 more
doaj +1 more source
Murine iNKT cells are depleted by liver damage via activation of P2RX7
European Journal of Immunology, Volume 50, Issue 10, Page 1515-1524, October 2020., 2020 Drug‐induced liver injury activates a suicide pathway in hepatic iNKT cells. The tissue damage induced release of ATP and NAD into the extracellular space triggers the receptor P2RX7 and leads locally to a long‐lasting depletion of iNKT cells. Abstract Invariant natural killer T cells (iNKT) constitute up to 50% of liver lymphocytes and contribute to ...
Astrid A. Bovens +6 more
wiley +1 more source
Molecules, 2023 In this study, three types of sulfonic acid group functionalized ionic liquids (SAILs) with a different number of catalytic groups and lipophilicity were synthesized and characterized by FT-IR, NMR, and MS analyses.
Thu Huong Nguyen Thi +5 more
doaj +1 more source