Results 221 to 230 of about 11,490,346 (250)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Systematic Screening of Tryptophan Metabolism Identifies Site- and Microbiota-Dependent Signatures of Tryptophan Utilization in Experimental Colitis. [PDF]

Int J Tryptophan Res
Wehkamp L, Alsaadi AI, Harris DMM, Yu M, Mekdoud T, Bornhäuser J, Springer E, Gilloteau C, Pothakamury AA, Smith JD, Jenkins BC, Guggeis M, Sommer F, Waschina S, Rosenstiel P, Schreiber S, McReynolds MR, Aden K.   +17 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Rewiring the mitochondrial NAD⁺-CoQ axis using metabolic nanomedicine for acute kidney injury therapy. [PDF]

Mater Today Bio
Ding H, Huang X, Hu P, Zhang X, Wang Y, Mao B, Ye J, Song D, Zhang C, Wang C.   +9 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Aerobic exercise combined with FK866 ameliorates Alzheimer's disease-like pathology in APP/PS1 mice with NAMPT abnormality. [PDF]

Front Immunol
Sun C, Zhang T, Fan B, Zhang X, Zhao N.
europepmc   +1 more source

Kynšperk nad Ohří 750 let 1232-1982

, 1982
Kynšperk nad Ohři
core  

Targeting the NAD+ Salvage Pathway Blocks Metabolic Recovery and Enhances β-Lapachone Toxicity in NQO1-Expressing Glioblastoma Cells. [PDF]

Cancer Res Commun
Chang-Gu B, Baljinnyam T, Sowers ML, Dilawari R, Herring J, Sowers L.   +5 more
europepmc   +1 more source

Label-Free Monitoring of Cancer-Associated Fibroblast Activation Using NAD(P)H Fluorescence Lifetime Imaging. [PDF]

Chembiochem
Anseeuw N, Escalona-Noguero C, Vankevelaer G, Aytekin S, De Wever O, Elia I, Rocha S, Solís-Fernández G.   +7 more
europepmc   +1 more source

Therapeutic Potential of Intra-Articular Delivery of Allogeneic Dedifferentiated Fat Cells in a Canine Monoiodoacetate-Induced Knee Osteoarthritis Model. [PDF]

Cells
Nakano R, Seki A, Sugiya H.
europepmc   +1 more source