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Biphasic Oxidation of Mitochondrial NAD(P)H
Biochemical and Biophysical Research Communications, 2002The redox state of mitochondrial pyridine nucleotides is known to be important for structural integrity of mitochondria. In this work, we observed a biphasic oxidation of endogenous NAD(P)H in rat liver mitochondria induced by tert-butylhydroperoxide. Nearly 85% of mitochondrial NAD(P)H was rapidly oxidized during the first phase.
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Reduction by a model of NAD(P)H
Bioorganic Chemistry, 1980Abstract Kinetics for the reduction of 2-acetylpyridine and 2-benzoylpyridine with 1-benzyl-1,4-dihydronicotinamide in acetonitrile has been studied. Isotope effects of the reduction reveal that the transfer of hydrogen nucleus is involved in the rate-determining step.
Atsuyoshi Ohno +4 more
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Reducing NAD(H) to amplify rhythms
Nature Metabolism, 2021Karthikeyani Chellappa, Joseph A. Baur
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Interconversion of NAD(H) TO NADP(H)
Biochemical Pharmacology, 1989Colin R. Stubberfield, Gerald M. Cohen
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2015
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NAD + Metabolism in Cardiac Health, Aging, and Disease
Circulation, 2021Mahmoud Abdellatif +2 more
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Regulation of NAD+ metabolism in aging and disease
Metabolism: Clinical and Experimental, 2022Xiaogang Chu, Raghavan Raju
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NAD+ metabolism and its roles in cellular processes during ageing
Nature Reviews Molecular Cell Biology, 2020Anthony J Covarrubias +2 more
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NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
Cell Metabolism, 2021Dan Ye, Yufei He, Hongyang Wang
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