Results 31 to 40 of about 158,023 (302)

Vitamins Reverse Endothelial Dysfunction Through Regulation of eNOS and NAD(P)H Oxidase Activities [PDF]

open access: yes, 2003
Antioxidant vitamins C and E have protective properties in genetic hypertension associated with enhanced oxidative stress. This study investigated whether vitamins C and/or E modulate vascular function by regulating enzymatic activities of endothelial ...
Ulker, S.   +4 more
core   +1 more source

NAD(P)H Oxidase [PDF]

open access: yesCirculation Research, 2000
Abstract —Reactive oxygen species have emerged as important molecules in cardiovascular function. Recent work has shown that NAD(P)H oxidases are major sources of superoxide in vascular cells and myocytes. The biochemical characterization, activation paradigms, structure, and function of this enzyme are now partly understood ...
K K, Griendling   +2 more
openaire   +2 more sources

Improved soluble expression and use of recombinant human renalase.

open access: yesPLoS ONE, 2020
Electrochemical bioreactor systems have enjoyed significant attention in the past few decades, particularly because of their applications to biobatteries, artificial photosynthetic systems, and microbial electrosynthesis.
Clifford S Morrison   +11 more
doaj   +1 more source

Simultaneous NAD(P)H and FAD fluorescence lifetime microscopy of long UVA–induced metabolic stress in reconstructed human skin

open access: yesScientific Reports, 2021
Solar ultraviolet longwave UVA1 exposure of human skin has short-term consequences at cellular and molecular level, leading at long-term to photoaging. Following exposure, reactive oxygen species (ROS) are generated, inducing oxidative stress that might ...
Thi Phuong Lien Ung   +10 more
doaj   +1 more source

NAD(P)+–NAD(P)H Model. 62. The Mechanism of the Silica Gel-Catalyzed Reduction with an NAD(P)H Model [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1987
Abstract The reduction of diethyl acetylenedicarboxylate, diethyl fumarate, and diethyl maleate as well as several α,β-unsaturated carbonyl compounds by a model of NAD(P)H on silica gel was examined. The order of the reactivity for the reduction was reverse to that of the degree of adsorption of the substrates onto the surface of silica ...
Shinro Yasui   +3 more
openaire   +1 more source

Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI

open access: yesBMC Nephrology, 2020
Background Preclinical studies have identified both NAD+ and sirtuin augmentation as potential strategies for the prevention and treatment of AKI. Nicotinamide riboside (NR) is a NAD+ precursor vitamin and pterostilbene (PT) is potent sirtuin activator ...
Petra Simic   +5 more
doaj   +1 more source

Ex Vivo Lung Perfusion with β-Nicotinamide Adenine Dinucleotide (NAD+) Improves Ischemic Lung Function

open access: yesAntioxidants, 2022
Ischemia-reperfusion injury compromises short- and long-term outcomes after lung transplantation. The scarce existing data on NAD+ suggest effects on hypoxia-induced vasoconstriction, on reactive oxygen species and on tampering inflammation.
Jonas Peter Ehrsam   +5 more
doaj   +1 more source

Nitric oxide synthase and NAD(P)H oxidase modulate coronary endothelial cell growth [PDF]

open access: yes, 2004
Reactive oxygen species (ROS) including nitric oxide (NO) and superoxide anion (O2-) are associated with cell migration, proliferation and many growth-related diseases.
U Bayraktutan, Bayraktutan, Ulvi
core   +1 more source

A nonrandomized study of single oral supplementation within the daily tolerable upper level of nicotinamide affects blood nicotinamide and NAD+ levels in healthy subjects

open access: yesTranslational Medicine of Aging, 2020
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple organisms, including humans. We report a human clinical trial designed to assess the efficacy of single-dose supplementation of nicotinamide, a form of ...
Takashi K. Ito   +12 more
doaj   +1 more source

A novel whole-cell biocatalyst with NAD+ regeneration for production of chiral chemicals. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: The high costs of pyridine nucleotide cofactors have limited the applications of NAD(P)-dependent oxidoreductases on an industrial scale.
Zijun Xiao   +8 more
doaj   +1 more source

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