Results 21 to 30 of about 158,023 (302)
NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism. [PDF]
Antioxid Redox Signal, 2018 The nicotinamide adenine dinucleotide (NAD+)/reduced NAD+ (NADH) and NADP+/reduced NADP+ (NADPH) redox couples are essential for maintaining cellular redox homeostasis and for modulating numerous biological events, including cellular metabolism. Deficiency or imbalance of these two redox couples has been associated with many pathological disorders ...
Xiao W, Wang RS, Handy DE, Loscalzo J.
europepmc +4 more sources
A Pathway for Repair of NAD(P)H in Plants [PDF]
Journal of Biological Chemistry, 2014 Unwanted enzyme side reactions and spontaneous decomposition of metabolites can lead to a build-up of compounds that compete with natural enzyme substrates and must be dealt with for efficient metabolism. It has recently been realized that there are enzymes that process such compounds, formulating the concept of metabolite repair.
Colinas Martinez, Maite Felicitas +5 more
openaire +4 more sources
Cytochemical Localization of NAD (P) H Oxidase in the Myoepithelial Cells of Salivary and Other Exocrine Glands [PDF]
, 1995 Cytochemical localization of NAD (P) H oxidase, a hydrogen-peroxide generating enzyme, has been investigated using the cerium method in several mammalian exocrine glands: (a) salivary glands of the rat, Mongolian gerbil, house musk shrew and man, (b ...
Yasuhisa Inoue +5 more
core +1 more source
Metabolic engineering of Escherichia coli for l-malate production anaerobically
Microbial Cell Factories, 2020 Background l-malate is one of the most important platform chemicals widely used in food, metal cleaning, textile finishing, pharmaceuticals, and synthesis of various fine chemicals. Recently, the development of biotechnological routes to produce l-malate
Youming Jiang +7 more
doaj +1 more source
Metabolic changes associated with dark-induced leaf senescence in Arabidopsis nadk2 mutants
Plant Signaling & Behavior, 2023 Arabidopsis NADK2 (NAD kinase 2) is a chloroplast-localized enzyme involved in NADP+ synthesis, which acts as the final electron acceptor in the photosynthetic electron transfer chain.
chaomurilege +5 more
doaj +1 more source
Frontiers in Physiology, 2016 Natural indicators provide intrinsic probes of metabolism, biogenesis and oxidative protection. Nicotinamide adenine dinucleotide metabolites (NAD(P)) are one class of indicators that have roles as co-factors in oxidative phosphorylation, glycolysis and ...
Kevin eConley +4 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2020 Cytotoxic effects of menadione on normal and cytochrome c-deficient yeast cells were examined on the basis of the cell growth rate, NAD(P)H concentration, reactive oxygen production, plasma membrane H+-ATPase activity, and ethanol production.
Shiro Yamashoji +2 more
doaj +1 more source
Changes in oxidative damage, inflammation and [NAD(H)] with age in cerebrospinal fluid. [PDF]
PLoS ONE, 2014 An extensive body of evidence indicates that oxidative stress and inflammation play a central role in the degenerative changes of systemic tissues in aging.
Jade Guest +3 more
doaj +1 more source
Translational Medicine of Aging, 2021 A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple species, including humans. Our previous clinical trial showed that supplementation of 200 mg nicotinamide, a form of vitamin B3, increased blood NAD+ levels.
Takashi K. Ito +6 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2019 Accumulating evidence suggests that active maintenance of optimal levels of the essential pyridine nucleotide, nicotinamide adenine dinucleotide (NAD+) is beneficial in conditions of either increased NAD+ turnover or inadequate synthesis, including ...
Ross Grant +9 more
doaj +1 more source