Results 21 to 30 of about 11,490,346 (250)

Mitochondrial NAD(P)H in vivo: identifying natural indicators of oxidative phosphorylation in the 31P magnetic resonance spectrum.

Frontiers in Physiology, 2016
Natural indicators provide intrinsic probes of metabolism, biogenesis and oxidative protection. Nicotinamide adenine dinucleotide metabolites (NAD(P)) are one class of indicators that have roles as co-factors in oxidative phosphorylation, glycolysis and ...
Kevin eConley, Amir Safi Ali, Brandon eFlores, Sharon eJubrias, Eric eShankland   +4 more
doaj   +1 more source

Cytotoxic effects of menadione on normal and cytochrome c-deficient yeast cells cultivated aerobically or anaerobically

Biochemistry and Biophysics Reports, 2020
Cytotoxic effects of menadione on normal and cytochrome c-deficient yeast cells were examined on the basis of the cell growth rate, NAD(P)H concentration, reactive oxygen production, plasma membrane H+-ATPase activity, and ethanol production.
Shiro Yamashoji, Arafat Al Mamun, Latiful Bari   +2 more
doaj   +1 more source

Changes in oxidative damage, inflammation and [NAD(H)] with age in cerebrospinal fluid. [PDF]

PLoS ONE, 2014
An extensive body of evidence indicates that oxidative stress and inflammation play a central role in the degenerative changes of systemic tissues in aging.
Jade Guest, Ross Grant, Trevor A Mori, Kevin D Croft   +3 more
doaj   +1 more source

A single oral supplementation of nicotinamide within the daily tolerable upper level increases blood NAD+ levels in healthy subjects

Translational Medicine of Aging, 2021
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple species, including humans. Our previous clinical trial showed that supplementation of 200 mg nicotinamide, a form of vitamin B3, increased blood NAD+ levels.
Takashi K. Ito, Tomohito Sato, Yusuke Takanashi, Zinat Tamannaa, Takuya Kitamoto, Keiichi Odagiri, Mitsutoshi Setou   +6 more
doaj   +1 more source

A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+

Frontiers in Aging Neuroscience, 2019
Accumulating evidence suggests that active maintenance of optimal levels of the essential pyridine nucleotide, nicotinamide adenine dinucleotide (NAD+) is beneficial in conditions of either increased NAD+ turnover or inadequate synthesis, including ...
Ross Grant, Ross Grant, Ross Grant, Jade Berg, Richard Mestayer, Richard Mestayer, Nady Braidy, James Bennett, Susan Broom, James Watson   +9 more
doaj   +1 more source

Vitamins Reverse Endothelial Dysfunction Through Regulation of eNOS and NAD(P)H Oxidase Activities [PDF]

, 2003
Antioxidant vitamins C and E have protective properties in genetic hypertension associated with enhanced oxidative stress. This study investigated whether vitamins C and/or E modulate vascular function by regulating enzymatic activities of endothelial ...
Ulker, S., McKeown, Pascal, Bayraktutan, Ulvi, Bayraktutan, U., Ulker, Sible   +4 more
core   +1 more source

Improved soluble expression and use of recombinant human renalase.

PLoS ONE, 2020
Electrochemical bioreactor systems have enjoyed significant attention in the past few decades, particularly because of their applications to biobatteries, artificial photosynthetic systems, and microbial electrosynthesis.
Clifford S Morrison, Elena E Paskaleva, Marvin A Rios, Thomas R Beusse, Elaina M Blair, Lucy Q Lin, James R Hu, Aidan H Gorby, David R Dodds, William B Armiger, Jonathan S Dordick, Mattheos A G Koffas   +11 more
doaj   +1 more source

Homogeneous nucleation of NAD and NAT in liquid stratospheric aerosols: insufficient to explain denitrification [PDF]

, 2002
Knopf DA, Koop T, Luo BP, Weers UG, Peter T. Homogeneous nucleation of NAD and NAT in liquid stratospheric aerosols: insufficient to explain denitrification. ATMOSPHERIC CHEMISTRY AND PHYSICS. 2002;2(3):207-214.The nucleation of NAD and NAT from HNO3/H2O
U. G. Weers, Luo, B. P., B. P. Luo, T. Peter, Weers, U. G., Koop, T., Koop, Thomas ; https://orcid.org/, Peter, T., T. Koop, Knopf, D. A., D. A. Knopf   +10 more
core   +2 more sources

Ex Vivo Lung Perfusion with β-Nicotinamide Adenine Dinucleotide (NAD⁺) Improves Ischemic Lung Function

Antioxidants, 2022
Ischemia-reperfusion injury compromises short- and long-term outcomes after lung transplantation. The scarce existing data on NAD+ suggest effects on hypoxia-induced vasoconstriction, on reactive oxygen species and on tampering inflammation.
Jonas Peter Ehrsam, Jin Chen, Hector Rodriguez Cetina Biefer, Isabelle Opitz, Stephan Arni, Ilhan Inci   +5 more
doaj   +1 more source

Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI

BMC Nephrology, 2020
Background Preclinical studies have identified both NAD+ and sirtuin augmentation as potential strategies for the prevention and treatment of AKI. Nicotinamide riboside (NR) is a NAD+ precursor vitamin and pterostilbene (PT) is potent sirtuin activator ...
Petra Simic, Xavier Fernando Vela Parada, Samir M. Parikh, Ryan Dellinger, Leonard P. Guarente, Eugene P. Rhee   +5 more
doaj   +1 more source