Hole hopping through tyrosine/tryptophan chains protects proteins from oxidative damage [PDF]
, 2015 Living organisms have adapted to atmospheric dioxygen by exploiting its oxidizing power while protecting themselves against toxic side effects. Reactive oxygen and nitrogen species formed during oxidative stress, as well as high-potential reactive ...
Gray, Harry B., Winkler, Jay R.
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ChemistryEurope, Volume 3, Issue 5, September 18, 2025.A standalone enzyme, derived from the reductase domain of a polyketide synthase‐nonribosomal peptide synthetase hybrid enzyme, is identified as a pyrroline carboxylate reductase. This enzyme is involved in the biosynthesis of 3‐methylproline, an amino acid building block of a unique tricyclic pyrrolizidinone structure of a fungal metabolite ...
Naoki Kato +6 more
wiley +1 more source
The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen [PDF]
, 2014 BACKGROUND: The facultatively anaerobic betaproteobacterium Castellaniella defragrans 65Phen utilizes acyclic, monocyclic and bicyclic monoterpenes as sole carbon source under oxic as well as anoxic conditions.
Becher, D. +7 more
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A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases [PDF]
, 2017 The ability to control enzymatic nicotinamide cofactor utilization is critical for engineering efficient metabolic pathways. However, the complex interactions that determine cofactor-binding preference render this engineering particularly challenging ...
Arnold, Frances H. +5 more
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Metabolic network analysis reveals microbial community interactions in anammox granules. [PDF]
, 2017 Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater.
Bhattacharjee, Ananda S +6 more
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Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells. [PDF]
, 2018 Neomorphic mutations in NADP-dependent isocitrate dehydrogenases (IDH1 and IDH2) contribute to tumorigenesis in several cancers. Although significant research has focused on the hypermethylation phenotypes associated with (D)2-hydroxyglutarate (D2HG ...
Badur, Mehmet G +8 more
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Recent Advances in Cofactor Regeneration Systems Applied to Biocatalyzed Oxidative Processes [PDF]
, 2012 Gotor Santamaría, Vicente Miguel +2 more
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Alcohol Dehydrogenase from Lactobacillus brevis: A Versatile Robust Catalyst for Enantioselective Transformations [PDF]
, 2011 The alcohol dehydrogenase from Lactobacillus brevis (LbADH) is a versatile catalyst for enantioselective reduction of ketones. Its substrate scope is wide with high regio- and enantioselectivity.
L. Greiner, S. Leuchs
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Inaktivierung mikrosomaler Proteine durch Lysosomen [PDF]
, 1973 Betz, Heinrich +2 more
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