Results 61 to 70 of about 8,934 (160)
The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen [PDF]
, 2014 BACKGROUND: The facultatively anaerobic betaproteobacterium Castellaniella defragrans 65Phen utilizes acyclic, monocyclic and bicyclic monoterpenes as sole carbon source under oxic as well as anoxic conditions.
Becher, D. +7 more
core +2 more sources
Advances in ethanol production [PDF]
, 2011 Barriers to the commercialization of lignocellulosic ethanol include the development of more robust biocatalysts, reduction of cellulase costs, and high capital cost associated with a complex process.
Geddes, Claudia-C +2 more
core +1 more source
From isolation to insights: mitochondrial complex I in the diatom Phaeodactylum tricornutum
The Plant Journal, Volume 125, Issue 3, February 2026.SUMMARY Diatoms are among the most ecologically successful microalgae, contributing significantly to marine primary production and global carbon cycling. Their distinctive metabolic architecture, shaped by a complex evolutionary history involving secondary endosymbiosis, includes a highly compartmentalized cell organization and unique metabolic ...
Federico Berdun +7 more
wiley +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Advanced Science, Volume 13, Issue 4, 19 January 2026.Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase
Advanced Science, Volume 13, Issue 4, 19 January 2026.Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song +9 more
wiley +1 more source
A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases [PDF]
, 2017 The ability to control enzymatic nicotinamide cofactor utilization is critical for engineering efficient metabolic pathways. However, the complex interactions that determine cofactor-binding preference render this engineering particularly challenging ...
Arnold, Frances H. +5 more
core +2 more sources
Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.Cardiac bioenergetic and metabolic perturbations in late‐stage Leigh syndrome. Whole‐body NDUFS4 loss severely impairs cardiac complex I activity and respiration, shifting reliance to complex II and reducing glycolytic, TCA, and amino acid‐derived energy‐generating substrates in the heart.
Karin Terburgh +2 more
wiley +1 more source
Metabolic network analysis reveals microbial community interactions in anammox granules. [PDF]
, 2017 Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater.
Bhattacharjee, Ananda S +6 more
core +2 more sources
NRF2 signalling in cytoprotection and metabolism
British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami +4 more
wiley +1 more source
Chemoenzymatic Asymmetric Synthesis of 1,4-Benzoxazine Derivatives: Application in the Synthesis of a Levofloxacin Precursor [PDF]
, 2015 Financial support of this work by the Spanish Ministerio de Ciencia e Innovación (MICINN) through the CTQ-2011-24237 and CTQ-2013-44153-P projects is grateful acknowledged. M. L.-I.
Busto García, Benjamín Eduardo +3 more
core +2 more sources