Results 71 to 80 of about 8,934 (160)

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

Cell Proliferation, Volume 59, Issue 1, January 2026.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng, Xin Ge, Chi Zhang, Xingye Yang, Zhengxin Yu, Min Zhang, Wen Cao, Qingtao Ni, Yang Liu, Songbing He, Yin Yuan   +10 more
wiley   +1 more source

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells. [PDF]

, 2018
Neomorphic mutations in NADP-dependent isocitrate dehydrogenases (IDH1 and IDH2) contribute to tumorigenesis in several cancers. Although significant research has focused on the hypermethylation phenotypes associated with (D)2-hydroxyglutarate (D2HG ...
Badur, Mehmet G, Cordes, Thekla, Guan, Kun-Liang, Ma, Shenghong, Magana, Jose H, McBrayer, Samuel K, Metallo, Christian M, Muthusamy, Thangaselvam, Parker, Seth J   +8 more
core  

Recent Advances in Cofactor Regeneration Systems Applied to Biocatalyzed Oxidative Processes [PDF]

, 2012
Gotor Santamaría, Vicente Miguel, Lavandera García, Iván, Rodríguez González, Cristina   +2 more
core   +1 more source

Alcohol Dehydrogenase from Lactobacillus brevis: A Versatile Robust Catalyst for Enantioselective Transformations [PDF]

, 2011
The alcohol dehydrogenase from Lactobacillus brevis (LbADH) is a versatile catalyst for enantioselective reduction of ketones. Its substrate scope is wide with high regio- and enantioselectivity.
L. Greiner, S. Leuchs
core   +1 more source

Redox-dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells. [PDF]

FEBS Lett
Blacker TS, Mistry N, Plotegher N, Westbrook ER, Sewell MDE, Carroll J, Szabadkai G, Bain AJ, Duchen MR.   +8 more
europepmc   +2 more sources

Pituitary 5 alpha-dihydroprogesterone 3 alpha-hydroxysteroid oxidoreductases. Subcellular location and properties of NADH- and NADPH-linked activities.

Journal of Biological Chemistry, 1980
J E, Krause, H J, Karavolas
openaire   +2 more sources

Inaktivierung mikrosomaler Proteine durch Lysosomen [PDF]

, 1973
Betz, Heinrich, Gratzl, Manfred, Remmer, Herbert   +2 more
core   +1 more source

Characterization of NADH Oxidase/NADPH Polysulfide Oxidoreductase and Its Unexpected Participation in Oxygen Sensitivity in an Anaerobic Hyperthermophilic Archaeon

Characterization of NADH Oxidase/NADPH Polysulfide Oxidoreductase and Its Unexpected Participation in Oxygen Sensitivity in an Anaerobic Hyperthermophilic Archaeon
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Integrated amplification of NADPH-regenerating modules enhances cytidine biosynthesis in <i>Escherichia coli</i>. [PDF]

Synth Syst Biotechnol
Liu L, Zhang X, Zhu T, Ye T, Li Z, Ding W, Liu H, Fang H.   +7 more
europepmc   +1 more source

Regeneration of cofactor NAD(P)⁺ with NAD(P)H oxidase for the production of value-added chemicals. [PDF]

Front Bioeng Biotechnol
Zhou LJ, Long SX, Huan T, Wu Y, Zhang YW.   +4 more
europepmc   +1 more source