Results 111 to 120 of about 1,272 (167)

Nicotinamide metabolism-related signature and lncRNA regulatory network in kidney renal clear cell carcinoma. [PDF]

PeerJ
Dong P, Zhao L, Shi P, Ma M, Huang B, Wang Z, Zhang S, Liu H.   +7 more
europepmc   +1 more source

Therapeutic targeting in breast cancer for the treatment of lymph node metastasis: MUTYH.

Metastasis is the major cause of death from cancer.  Metastasis to the lymph node (“regional” metastasis) generally precedes distant metastasis, and we recently demonstrated that metastasis to the lymph nodes is a likely prerequisite for metastasis to the central nervous system (CNS) in humans with breast cancer (1-8).
openaire   +31 more sources

Synthesis of thermostable artificial nicotinamide cofactors: carba-NAD⁺ and carba-NADP^. [PDF]

RSC Chem Biol
Dsouza Z, Friedrichs JJ, Döring M, Rincón Téllez N, Schmermund L, Sieber V.   +5 more
europepmc   +1 more source

PROBING BINDING REQUIREMENTS OF NAD KINASE WITH MODIFIED NAD ANALOGUES

, 2012
NAD kinase (NADK) catalyzes a magnesium-dependent phosphorylation of the 2′-hydroxyl group of the adenosine ribose moiety of nicotinamide adenine dinucleotide (NAD) using ATP or inorganic polyphosphates as phosphoryl donors to give NADP.
Michele Di Stefano, Palmarisa Franchetti, Krzysztof W. Pankiewicz, CAPPELLACCI, Loredana, VITA, PATRIZIA, Mario Grifantini, Giulio Magni, PETRELLI, Riccardo, TORQUATI, ILARIA, Krzysztof Felczak   +9 more
core  

Oxidative Stress Induces the Phosphorylation of NAD⁺ to NADP⁺ by NAD Kinase in Cultured Primary Rat Astrocytes. [PDF]

Neurochem Res
Willker JE, Watermann P, Dringen R.
europepmc   +1 more source

Kinase and phosphatase inhibition as a signal transduction-centric approach to adjunctive chemotherapies for the treatment of gynecologic cancers: DTYMK.

Men and women differ in large part resulting from the presence or absence of gynecologic organs including the ovaries, the uterus, the lining of which is known as the endometrium, and the entry to the uterus (womb), the cervix (1), all of which are targets for development of malignancies (2-7); vulvar cancer is less common (8).
openaire   +11 more sources

Cracking the Code of Cardiac ATP-Dependent Citrate Lyase With Wet and Dry Tools. [PDF]

Circulation
Walker MA, Tian R.
europepmc   +1 more source

Tandem repeat polymorphisms are associated with brain structure: results of two large population-based studies. [PDF]

Genome Med
Mantey R, Hu J, Touhidinia M, Butt T, Sidky AM, Sobhani R, Estrada S, Haendler K, De Domenico E, Beyer MD, Breteler MMB, Aziz NA.   +11 more
europepmc   +1 more source

β-Lapachone-Induced Oxidative Stress Causes PARP-Dependent NAD⁺-Depletion that Affects the Energy Metabolism of Cultured Primary Rat Astrocytes. [PDF]

Neurochem Res
Willker JE, Dringen R.
europepmc   +1 more source

Integrative Proteomic Profiling of Blood Pressure and Hypertension. [PDF]

Hypertension
Aggarwal M, Joehanes R, Huan T, Courchesne P, Dupuis J, O'Connor G, Levy D.   +6 more
europepmc   +1 more source