Results 101 to 110 of about 1,272 (167)

Data from NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non–Small Cell Lung Carcinoma

<div>Abstract<p>Osimertinib, a third generation epidermal growth factor receptor tyrosine kinase inhibitor, is approved as a first-line therapy in patients with advanced non–small cell lung carcinoma (NSCLC) with EGFR-activating mutations or the T790M resistance mutation.
Yunchong Meng, Yongde Liao, Xiaojun Wang, Peiyuan Mei, Kuo Li, Quanfu Huang, Mingxin Diao, Shihao Wu, Na Wang, Wei Lin   +9 more
openaire   +1 more source

Supplementary Table 11 from NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non–Small Cell Lung Carcinoma

<p>Supplementary Table 11 Detection of SNVs and CNVs in HCC827OR and PC9OR</p>
Yunchong Meng, Yongde Liao, Xiaojun Wang, Peiyuan Mei, Kuo Li, Quanfu Huang, Mingxin Diao, Shihao Wu, Na Wang, Wei Lin   +9 more
openaire   +1 more source

Unveiling blood pressure‐associated genes in aortic cells through integrative analysis of GWAS and RNA modification‐associated variants

Chronic Diseases and Translational Medicine
Background Genome‐wide association studies (GWAS) have identified more than a thousand loci for blood pressure (BP). Functional genes in these loci are cell‐type specific.
Huan Zhang, Yuxi Chen, Peng Xu, Dan Liu, Naqiong Wu, Laiyuan Wang, Xingbo Mo   +6 more
doaj   +1 more source

Identification and validation of NAD+ metabolism-related biomarkers in patients with diabetic peripheral neuropathy

Frontiers in Endocrinology
BackgroundThe mechanism of Nicotinamide Adenine Dinucleotide (NAD+) metabolism-related genes (NMRGs) in diabetic peripheral neuropathy (DPN) is unclear.
Chenhao Ye, Yuedong Fu, Xijie Zhou, Feiya Zhou, Xuwei Zhu, Yiheng Chen   +5 more
doaj   +1 more source

Systematic evolutionary relationships of 24 species among eight lineages within the supergroup Plantae.

, 2014
The numbers of NADK homologs in each species are listed next to the tree. *, the genome sequencing of Picea sitchensis is not complete.
Ri Li (589196), Wen-Qiang Li (589197), Xiang Wang (127867), Wen-Yan Li (589195), Kun-Ming Chen (589198)   +4 more
core   +1 more source

Staphylococcus aureus NAD kinase is required for envelop and antibiotic stress responses

International audienceGlobal burden of infectious diseases and antimicrobial resistance are major public health issues calling for innovative control measures. Bacterial NAD kinase (NADK) is a crucial enzyme for production of NADP(H) and growth.
Mondange, Lou, Pizarro-Cerdá, Javier, Leseigneur, Clarisse, Dussurget, Olivier   +3 more
core   +1 more source

Regulation of NAD kinase in neutrophils

, 2016
NADP+ and NADPH are involved in many biosynthetic pathways and signal transduction mechanisms. NAD kinase (NADK) is the only known enzyme that catalyzes the de novo synthesis of NADP+ from NAD+.
Rabani, Razieh
core  

(−)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase

Nicotinamide adenine dinucleotide kinase (NADK) controls the intracellular NADPH content and provides reducing power for the synthesis of macromolecules and anti-ROS. Moreover, NADK is considered to be a synthetic lethal gene for KRAS mutations.
Bei Zhang (428038), Mingliang Wang (1666225), Cheng Luo (48047), Wenjia Shi (4726887), Naixia Zhang (474251), Qiqi Wu (4895728), Dean Guo (207402), Qi Li (67548), Tonghai Liu (3447899), Daohai Du (1714372), Bo Han (84102), Jie Zheng (31208), Yiluan Ding (10911999), Hao Zhang (15339)   +13 more
core   +1 more source

Collateral lethality of NAD kinase in 1p36 deleted tumors drives vulnerability to NAD kinase 2 depletion. [PDF]

BBA Adv
Suyama-Banjo S, Watanabe K, Ishikawa H, Yoshihama Y, Hirota Y, Tsutsumi S.   +5 more
europepmc   +1 more source

Metabolic engineering of <i>Escherichia coli</i> for efficient production of d-phenylglycine. [PDF]

Synth Syst Biotechnol
Xiong Y, Shang Z, Lu L, Wang T, Cai G, Shen X, Sun X, Wang J, Yuan Q.   +8 more
europepmc   +1 more source