Results 1 to 10 of about 138,614 (312)

NERNST: a genetically-encoded ratiometric non-destructive sensing tool to estimate NADP(H) redox status in bacterial, plant and animal systems

open access: yesNature Communications, 2023
NADP(H) is a central metabolic hub providing reducing equivalents to multiple biosynthetic, regulatory and antioxidative pathways in all living organisms.
Pamela E. Molinari   +14 more
doaj   +2 more sources

Nanomechanical Study of Enzyme: Coenzyme Complexes: Bipartite Sites in Plastidic Ferredoxin-NADP+ Reductase for the Interaction with NADP+

open access: yesAntioxidants, 2022
Plastidic ferredoxin-NADP+ reductase (FNR) transfers two electrons from two ferredoxin or flavodoxin molecules to NADP+, generating NADPH. The forces holding the Anabaena FNR:NADP+ complex were analyzed by dynamic force spectroscopy, using WT FNR and ...
Sandra Pérez-Domínguez   +5 more
doaj   +2 more sources

Inter-Organelle NAD Metabolism Underpinning Light Responsive NADP Dynamics in Plants

open access: yesFrontiers in Plant Science, 2019
Upon illumination, photosystem I in chloroplasts catalyzes light-driven electron transport from plastocyanin to ferredoxin, followed by the reduction of NADP+ to NADPH by ferredoxin:NADP+ reductase for CO2 fixation.
Shin-nosuke Hashida, Maki Kawai-Yamada
doaj   +2 more sources

A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes

open access: yesNature Communications
The NADPH/NADP+ redox couple is central to metabolism and redox signalling. NADP redox state is differentially regulated by distinct enzymatic machineries at the subcellular compartment level.
Marie Scherschel   +22 more
doaj   +2 more sources

Auxin is involved in arbuscular mycorrhizal fungi-promoted tomato growth and NADP-malic enzymes expression in continuous cropping substrates

open access: yesBMC Plant Biology, 2021
Background Despite significant limitations of growth medium reuse, a large amount of organic substrate is reused in soilless cultivation of horticultural crops in China. Arbuscular mycorrhizal fungi (AMF) can promote nutrient absorption and improve plant
Yu Wang   +7 more
doaj   +2 more sources

NADP-Dependent Malic Enzyme 1 Participates in the Abscisic Acid Response in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2018
Arabidopsis thaliana possesses three cytosolic (NADP-ME1-3) and one plastidic (NADP-ME4) NADP-dependent malic enzymes. NADP-ME2 and -ME4 show constitutive expression, in contrast to NADP-ME1 and -ME3, which are restricted to particular tissues.
Cintia L. Arias   +9 more
doaj   +2 more sources

NADP+ is an endogenous PARP inhibitor in DNA damage response and tumor suppression

open access: yesNature Communications, 2019
Cancer cells respond differently to inhibitors of Poly (ADP-ribose) polymerase. Here the authors reveal that ovarian cancer cells with higher cellular NADP+ levels are more sensitive to clinically relevant PARP1 inhibitors and show that NADP+ act as an ...
Chunjing Bian   +9 more
doaj   +2 more sources

NADP-Dependent Isocitrate Dehydrogenase from Arabidopsis Roots Contributes in the Mechanism of Defence against the Nitro-Oxidative Stress Induced by Salinity

open access: yesThe Scientific World Journal, 2012
NADPH regeneration appears to be essential in the mechanism of plant defence against oxidative stress. Plants contain several NADPH-generating dehydrogenases including isocitrate dehydrogenase (NADP-ICDH), glucose-6-phosphate dehydrogenase (G6PDH), 6 ...
Marina Leterrier   +4 more
doaj   +2 more sources

Salinity Induces Granal Development in Bundle Sheath Chloroplasts of NADP-Malic Enzyme Type C4 Plants

open access: goldPlant Production Science, 2009
In NADP-malic enzyme (NADP-ME) type C4 plants, MC chloroplasts have well-developed grana, whereas BSC chloroplasts are generally characterized by highly reduced grana.
Eiji Omoto   +3 more
doaj   +2 more sources

The regulation and catalytic mechanism of the NADP-malic enzyme from tobacco leaves [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
The non-photosynthetic NADP-malic enzyme EC 1.1.1.40 (NADP-ME), which catalyzes the oxidative decarboxylation of L-malate and NADP+ to produce pyruvate and NADPH, respectively, and which could be involved in plant defense responses, was isolated from ...
Doubnerová Veronika   +3 more
doaj   +3 more sources

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