NADP-Dependent Malic Enzyme 1 Participates in the Abscisic Acid Response in Arabidopsis thaliana [PDF]
Frontiers in Plant Science, 2018 Arabidopsis thaliana possesses three cytosolic (NADP-ME1-3) and one plastidic (NADP-ME4) NADP-dependent malic enzymes. NADP-ME2 and -ME4 show constitutive expression, in contrast to NADP-ME1 and -ME3, which are restricted to particular tissues.
Cintia L. Arias +9 more
doaj +6 more sources
NERNST: a genetically-encoded ratiometric non-destructive sensing tool to estimate NADP(H) redox status in bacterial, plant and animal systems [PDF]
Nature Communications, 2023 NADP(H) is a central metabolic hub providing reducing equivalents to multiple biosynthetic, regulatory and antioxidative pathways in all living organisms.
Pamela E. Molinari +14 more
doaj +3 more sources
The regulation and catalytic mechanism of the NADP-malic enzyme from tobacco leaves [PDF]
Journal of the Serbian Chemical Society, 2009 The non-photosynthetic NADP-malic enzyme EC 1.1.1.40 (NADP-ME), which catalyzes the oxidative decarboxylation of L-malate and NADP+ to produce pyruvate and NADPH, respectively, and which could be involved in plant defense responses, was isolated from ...
VERONIKA DOUBNEROVÁ +3 more
doaj +5 more sources
A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes [PDF]
Nature CommunicationsThe NADPH/NADP+ redox couple is central to metabolism and redox signalling. NADP redox state is differentially regulated by distinct enzymatic machineries at the subcellular compartment level.
Marie Scherschel +22 more
doaj +2 more sources
Dynamic and Static Regulation of Nicotinamide Adenine Dinucleotide Phosphate: Strategies, Challenges, and Future Directions in Metabolic Engineering [PDF]
MoleculesReduced nicotinamide adenine dinucleotide phosphate (NADPH) is a crucial cofactor in metabolic networks. The efficient regeneration of NADPH is one of the limiting factors for productivity in biotransformation processes.
Nana Ding +3 more
doaj +2 more sources
NADP(H) allosterically regulates the interaction between ferredoxin and ferredoxin‐NADP+ reductase [PDF]
FEBS Open Bio, 2019 Ferredoxin‐NADP+ reductase (FNR) in plants receives electrons from ferredoxin (Fd) at the end of the photosynthetic electron transfer chain and converts NADP+ to NADPH. The interaction between Fd and FNR in plants was previously shown to be attenuated by
Yoko Kimata‐Ariga +6 more
doaj +3 more sources
NADP-malic Enzyme OsNADP-ME2 Modulates Plant Height Involving in Gibberellin Signaling in Rice [PDF]
RicePlants NADP-malic enzymes (NADP-MEs) act as a class of oxidative decarboxylase to mediate malic acid metabolism in organisms. Despite NADP-MEs have been demonstrated to play pivotal roles in regulating diverse biological processes, the role of NADP-MEs ...
Bing Li +13 more
doaj +2 more sources
MAT2B regulates the protein level of MAT2A to preserve RNA N6-methyladenosine [PDF]
Cell Death and DiseaseMAT2B works together with MAT2A to synthesize S-Adenosyl methionine (SAM) as the primary methyl donor. MAT2B, despite lacking catalytic activity, exerts regulatory control over the enzymatic activity of MAT2A.
Xinyi Wan +14 more
doaj +2 more sources
Adjustment of light-responsive NADP dynamics in chloroplasts by stromal pH
Nature Communications, 2023 Cyclic electron transfer (CET) predominates when NADP+ is at basal levels, early in photosynthetic induction; however, the mechanism underlying the subsequent supply of NADP+ to fully drive steady-state linear electron transfer remains unclear.
Yusuke Fukuda +3 more
doaj +1 more source
NADP(H)-dependent biocatalysis without adding NADP(H)
Proceedings of the National Academy of Sciences, 2022 Isocitrate dehydrogenase 1 (IDH1) naturally copurifies and crystallizes in a resting state with a molecule of its exchangeable cofactor, NADP + /NADPH, bound in each monomer of the homodimer. We report electrochemical studies with IDH1 that exploit this property to reveal the massive advantage of nanoconfinement to ...
Herold, RA +3 more
openaire +2 more sources