Results 111 to 120 of about 10,930 (224)

Myeloid HDAC7 drives liver inflammation and systemic glucose dysregulation during diet‐induced obesity

open access: yesClinical &Translational Immunology, Volume 15, Issue 6, 2026.
This study explored the role of the class IIa histone deacetylase HDAC7 in hepatic inflammation and metabolic disease. Genetic approaches in mice revealed that myeloid HDAC7 drives hepatic inflammation and gene signatures associated with advanced chronic liver disease.
Yizhuo Wang   +27 more
wiley   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang   +14 more
wiley   +1 more source

Evolution of Thiosemicarbazones: From First‐ to Second‐Generation Metal Chelators and Their Reactive Oxygen Species‐Mediated Effects in Melanoma

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Thiosemicarbazones (TSC) have demonstrated promise as new chemotherapeutic agents against melanoma in both in vitro and In vivo studies. TSC are powerful metal coordinating agents, coordinating transition metal ions such as zinc, copper and iron in multiple oxidation states. It is this metal coordination that imparts the anticancer activity.
Rohina Alim   +2 more
wiley   +1 more source

A putative approach for influencing stomatal density by over-expressing NADP-dependent malic enzyme in arabidopsis

open access: yes, 2007
Stomata are leaf structures critical for plant survival because they modulate the rate of transpiration. This study will examine a possible mode for regulating stomatal density by over-expressing NADP-dependent malic enzyme (NADP-ME), which is thought to
Gabor, Michael M
core  

Investigation of carbonic anhidrase 1 (ca 1) and malic enzyme (me) in acıpayam sheep by using starch gel electrophoresis [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Aim: For the determination of genetic structure of Acipayam Sheep, two enzyme loci were studied by using starch gel electrophoresis; carbonic anhidrase 1 (CA 1) and malic enzyme (ME).
Ümmühan Özdemir   +1 more
doaj  

Improved mesophyll–bundle sheath connectivity is achieved via different mechanisms in C2 vs C4 Alternanthera

open access: yesNew Phytologist, Volume 250, Issue 6, Page 3675-3686, June 2026.
Leaf anatomy and biochemistry of C3, C2, and C4 plants. Summary Connectivity between mesophyll (M) and bundle sheath (BS) cells must improve during the evolution of C4 photosynthesis to facilitate large metabolite fluxes between these cell types, but the trait combinations that enhance M–BS connectivity and the points at which these enhancements occur ...
Hattie R. Roberts   +4 more
wiley   +1 more source

Modalities of NADP-malic enzyme activities under light and darkness indicate its regulation with reference to C4 weed

open access: yes, 2020
NADP –ME is the key enzyme for decarboxylation reactions in C4 CO2 concentration pathways. So, Amaranthus viridis has been evaluated with regards to photosynthetic NADP-malic enzyme for its response under light and darkness.
Ghosh, Arijit   +5 more
core   +1 more source

Biochemical Studies of NADP-Malic Enzyme in Detached Pineapple (Ananas comosus cv Cayenne0 Fruits

open access: yes, 2014
本研究進行採收後開英種鳳梨 (Ananas comosus cv. Cayenne)果肉 NADP+-蘋果酸酵素(malate dehydrogenase, EC 1.1.1.40) 生化特性探討 。酵素萃取後,以40% polyehylene glycol 沉澱,依序經離子交換樹脂( DEAE-Sepharose)管柱層析及親合性(2'',5''-ADP Sepharose)純化,其比活
徐智鍵, Hsu, Chih-Chien
core  

ADAPTIVE RESPONSE OF ESCHERICHIA COLI TO ALKYLATING AGENTS: MOLECULAR ASPECTS AND BIOTECHNOLOGICAL APPLICATIONS IN THE BIOREMEDIATION FIELD

open access: yes, 2009
The increasingly stringent environmental regulations on hazardous wastes has encouraged the search for innovative solutions for the remediation of contaminated wastes.
Rippa, Valentina
core  

Coding nucleotide sequence of rat liver malic enzyme mRNA.

open access: yes, 1986
The nucleotide sequence of the mRNA for malic enzyme ((S)-malate NADP+ oxidoreductase (oxaloacetate-decarboxylating, EC 1.1.1.40) from rat liver was determined from three overlapping cDNA clones.
Magnuson MA   +3 more
core  

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