Results 31 to 40 of about 72,905 (323)

Biophysical characterization of the dimer and tetramer interface interactions of the human cytosolic malic enzyme. [PDF]

PLoS ONE, 2012
The cytosolic NADP(+)-dependent malic enzyme (c-NADP-ME) has a dimer-dimer quaternary structure in which the dimer interface associates more tightly than the tetramer interface. In this study, the urea-induced unfolding process of the c-NADP-ME interface
Sujithkumar Murugan, Hui-Chih Hung
doaj   +1 more source

Homeostatic regulation of NAD(H) and NADP(H) in cells

Genes and Diseases
Nicotinamide adenine dinucleotide (NAD+)/reduced NAD+ (NADH) and nicotinamide adenine dinucleotide phosphate (NADP+)/reduced NADP+ (NADPH) are essential metabolites involved in multiple metabolic pathways and cellular processes.
Luojun Chen, Xiaoke Xing, Pingfeng Zhang, Lulu Chen, Huadong Pei   +4 more
doaj   +1 more source

Increasing lipid production using an NADP+-dependent malic enzyme from Rhodococcus jostii.

Microbiology, 2019
The occurrence of NADP+-dependent malic enzymes (NADP+-MEs) in several Rhodococcus strains was analysed. The NADP+-ME number in Rhodococcus genomes seemed to be a strain-dependent property.
M. Hernández, H. Alvarez
semanticscholar   +1 more source

A STD-NMR Study of the Interaction of the Anabaena Ferredoxin-NADP+ Reductase with the Coenzyme

Molecules, 2014
Ferredoxin-NADP+ reductase (FNR) catalyzes the electron transfer from ferredoxin to NADP+ via its flavin FAD cofactor. To get further insights in the architecture of the transient complexes produced during the hydride transfer event between the enzyme ...
Lara V. Antonini, José R. Peregrina, Jesús Angulo, Milagros Medina, Pedro M. Nieto   +4 more
doaj   +1 more source

Shade compromises the photosynthetic efficiency of NADP-ME less than that of PEP-CK and NAD-ME C4 grasses

Journal of Experimental Botany, 2018
Photosynthesis and productivity are less compromised by low light in NADP-ME C4 grasses relative to PEP-CK and NAD-ME counterparts.
B. V. Sonawane, R. Sharwood, S. Whitney, O. Ghannoum   +3 more
semanticscholar   +1 more source

NADP+ reduction by human lymphocytes [PDF]

Clinical and Experimental Immunology, 1990
SUMMARY The hexose monophosphate shunt (HMPS) is known to be responsible for the reduction of NADP+ by lymphocytes. We tried to find other enzymatic systems that might provide the lymphocytes with NADPH. By measuring the absorbance at 340 nm we noted that the addition of NADP+ to a preparation of disrupted lymphocytes resulted in the ...
A. Klein, A. Malkin, A. W.-L. Chan, B. U. Caplan   +3 more
openaire   +3 more sources

NADPH-generating dehydrogenases: their role in the mechanism of protection against nitro-oxidative stress induced by adverse environmental conditions

Frontiers in Environmental Science, 2014
NADPH is an essential reductive coenzyme in biosynthetic processes such as cell growth, proliferation and detoxification in eukaryotic cells. It is required by antioxidative systems such as the ascorbate-glutathione cycle and is also necessary for the ...
Francisco Javier Corpas, Juan B Barroso
doaj   +1 more source

Photosynthetic nitrogen- and water-use efficiencies in C3 and C4 subtype grasses grown under two nitrogen supply levels

Plant Production Science, 2021
C4 plants have higher photosynthetic nitrogen- and water-use efficiencies (PNUE and PWUE) than C3 plants. Some studies on C4 grasses have reported that NADP-malic enzyme (NADP-ME) grasses have higher PNUE than NAD-malic enzyme (NAD-ME) grasses, whereas ...
Yuko Togawa-Urakoshi, Osamu Ueno
doaj   +1 more source

Engineering Cofactor Specificity of a Thermostable Phosphite Dehydrogenase for a Highly Efficient and Robust NADPH Regeneration System

Frontiers in Bioengineering and Biotechnology, 2021
Nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases catalyze a range of chemical reactions useful for practical applications. However, their dependence on the costly cofactor, NAD(P)H remains a challenge which must be addressed ...
Gamal Nasser Abdel-Hady, Gamal Nasser Abdel-Hady, Takeshi Ikeda, Takeshi Ikeda, Takenori Ishida, Takenori Ishida, Hisakage Funabashi, Hisakage Funabashi, Akio Kuroda, Akio Kuroda, Ryuichi Hirota, Ryuichi Hirota   +11 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source