Results 31 to 40 of about 56,076 (155)
Optimization of Enzymatic Gas-Phase Reactions by Increasing the Long-Term Stability of the Catalyst [PDF]
, 2004 Enzymatic gas-phase reactions are usually performed in continuous reactors, and thus very stable and active catalysts are required to perform such transformations on cost-effective levels.
Büchs, Jochen, +4 more
core +2 more sources
COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma
Advanced Science, EarlyView.COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo +15 more
wiley +1 more source
Characterisation of components and mechanisms involved in redox-regulation of protein import into chloroplasts [PDF]
, 2009 The vast majority of chloroplast proteins is encoded in the nucleus and thus has to be posttranslationally imported into the organelle, a process that is facilitated by two multimeric protein machineries, the Toc and Tic complexes (translocon at the ...
Stengel, Anna
core
Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis [PDF]
, 2015 Species-specific antimicrobial therapy has the potential to combat the increasing threat of antibiotic resistance and alteration of the human microbiome.
Chen, Weihau +7 more
core +5 more sources
Advanced Science, EarlyView.Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang +6 more
wiley +1 more source
Advanced Science, EarlyView.This study prepares copper tungstate (CuWO4, CWO) nanoparticles for synergistic sono‐enhanced cuproptosis‐based cancer therapy. With an ultrasmall bandgap (1.71 eV), CWO facilitates efficient charge carrier separation under ultrasound, enhancing the generation of reactive oxygen species and the controlled release of Cu2+ ions cascade amplify oxidative ...
Lichao Zhu +9 more
wiley +1 more source
Advanced Science, EarlyView.This study develops a photosynthetic bioelectrochemical nitrogen fixation system for simultaneous nitrogen fixation and current generation using Rhodopseudomonas palustris. Notably, extracellular electron transfer (EET) serves as a redox balancing strategy, suppressing nitrogen fixation by competing with nitrogenase for electrons.
Xuewen Liu +6 more
wiley +1 more source
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
National Atmospheric Deposition Program 2006 Annual Summary [PDF]
, 2007 published or submitted for publicationis peer ...
National Atmospheric Deposition Program
core
Evidence of the indirect hormonal activity of prohormones using liver S9 metabolic bioactivation and an androgen bioassay [PDF]
, 2008 Prohormones such as dehydroepiandrosterone (DHEA) are steroid precursors that do not show hormonal activity by themselves. Abuse of these prohormones in cattle fattening is hard to prove because of strong in vivo metabolism and the difficulty to detect ...
Bovee, T.F.H. +4 more
core +2 more sources