Results 141 to 150 of about 56,952 (277)

Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction

, 2015
Eukaryotic metabolism is organised in complex networks of enzyme catalysed reactions which are distributed over different organelles. To quantify the compartmentalised reactions, quantitative measurements of relevant physiological variables in different ...
Heijnen, J.J. (author), Zhang, J. (author), Daran, J.G., Ten Pierick, A. (author), Daran, J.G. (author), Maleki Seifar, R., Van Rossum, H.M., Wahl, S.A. (author), Van Rossum, H.M. (author), Maleki Seifar, R. (author), Wahl, S.A., Heijnen, J.J., Ten Pierick, A., Zhang, J.   +13 more
core   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

NADP ⁺ Reduction with Reduced Ferredoxin and NADP ⁺ Reduction with NADH Are Coupled via an Electron-Bifurcating Enzyme Complex in Clostridium kluyveri

, 2010
It was recently found that the cytoplasmic butyryl-coenzyme A (butyryl-CoA) dehydrogenase-EtfAB complex from Clostridium kluyveri couples the exergonic reduction of crotonyl-CoA to butyryl-CoA with NADH and the endergonic ...
Rudolf K. Thauer, Thauer, R., Wang, S., Moll, J., Johanna Moll, Huang, H., Shuning Wang, Haiyan Huang   +7 more
core   +1 more source

Fast & fuelious: the malate–aspartate shuttle in brown adipocyte lipid metabolism

The FEBS Journal, EarlyView.
Brown adipose tissue (BAT) produces heat in response to cold exposure, for which it relies on the coordination of aerobic and anaerobic metabolism. However, how reaction intermediates connect these two essential pathways is unclear. In this issue of The FEBS Journal, Veliova et al., report that the malate–aspartate shuttle (MAS) supports norepinephrine‐
Lukas Blaas, Alexander Bartelt
wiley   +1 more source

Spatiotemporal Regulation of the NADP(H) Phosphatase Nocturnin

, 2023
Periodic changes in the environment are ubiquitous in the natural world. Among these, the most biologically relevant rhythm is the 24-hour geophysical day/night cycle. As an adaptive strategy, many organisms have evolved an endogenous biological clock to
Laothamatas, Isara
core  

The multidimensional regulation roles and mechanisms of calcium in fruit quality

Journal of Integrative Plant Biology, EarlyView.
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang, Siyang Gao, Mengdi Li, Zeqi Zhao, Chengwei Yang, Ji‐Hong Liu, Chunlong Li   +6 more
wiley   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

Enzymreaktoren mit geladenen Membranen für die kontinuierliche Regeneration nativer Coenzyme. II. Synthese hydrophober Verbindungen durch NADP(H)-abhängige Dehydrogenasen

, 2022
S.643-647 : Abb.,Lit.Alcohol dehydrogenase, 12-alpha-hydroxysteroid dehydrogenase and glutamate dehydrogenase were succesfully used over long time periods in continuous experiments for stereospecific redox reactions.
Chmiel, H., Kulbe, K.-D., Hasenfratz, H., Schmidt, K., Röthig, T.R.   +4 more
core  

Kinetic parameter prediction using neural networks identifies limitations to C4 photosynthesis

New Phytologist, EarlyView.
Schematic overview of the generation of artificial training data and training of neural networks in C4TUNE. Summary Kinetic models of photosynthesis enable time‐resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis.
Philipp Wendering, John Ferguson, Rudan Xu, Johannes Kromdijk, Zoran Nikoloski   +4 more
wiley   +1 more source

Spatiotemporal regulation of NADP(H) phosphatase Nocturnin and its role in oxidative stress response. [PDF]

Proc Natl Acad Sci U S A, 2020
Laothamatas I, Gao P, Wickramaratne A, Quintanilla CG, Dino A, Khan CA, Liou J, Green CB.   +7 more
europepmc   +1 more source