Results 31 to 40 of about 11,248,301 (236)

Short-Term Low Temperature Induces Nitro-Oxidative Stress that Deregulates the NADP-Malic Enzyme Function by Tyrosine Nitration in Arabidopsis thaliana

Antioxidants, 2019
Low temperature (LT) negatively affects plant growth and development via the alteration of the metabolism of reactive oxygen and nitrogen species (ROS and RNS).
Juan C. Begara-Morales, Beatriz Sánchez-Calvo, María V. Gómez-Rodríguez, Mounira Chaki, Raquel Valderrama, Capilla Mata-Pérez, Javier López-Jaramillo, Francisco J. Corpas, Juan B. Barroso   +8 more
doaj   +1 more source

Change in Cofactor Specificity of Oxidoreductases by Adaptive Evolution of an Escherichia coli NADPH-Auxotrophic Strain

mBio, 2021
The nicotinamide cofactor specificity of enzymes plays a key role in regulating metabolic processes and attaining cellular homeostasis. Multiple studies have used enzyme engineering tools or a directed evolution approach to switch the cofactor preference
Madeleine Bouzon, Volker Döring, Ivan Dubois, Anne Berger, Gabriele M. M. Stoffel, Liliana Calzadiaz Ramirez, Sophia N. Meyer, Marion Fouré, David Roche, Alain Perret, Tobias J. Erb, Arren Bar-Even, Steffen N. Lindner   +12 more
doaj   +1 more source

Proposed mechanism of FMN-DI catalyzing the hydride transfer between NAD(H) and NADP(H).

, 2016
Proposed mechanism of FMN-DI catalyzing the hydride transfer between NAD(H) and NADP(H).
Fangfang Sun (2410654), Ting Zhang (102583), Jinglin Fu (225092), John Collins (1769020), Scott Huston (2657011), Y.-H. Percival Zhang (28712)   +5 more
core   +1 more source

Dynamic and Static Regulation of Nicotinamide Adenine Dinucleotide Phosphate: Strategies, Challenges, and Future Directions in Metabolic Engineering

Molecules
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is a crucial cofactor in metabolic networks. The efficient regeneration of NADPH is one of the limiting factors for productivity in biotransformation processes.
Nana Ding, Zenan Yuan, Lei Sun, Lianghong Yin   +3 more
doaj   +1 more source

Physiological Significance of NAD Kinases in Cyanobacteria

Frontiers in Plant Science, 2019
Unicellular cyanobacteria are thought to be the evolutionary ancestors of plant chloroplasts and are widely used both for chemical production and as model organisms in studies of photosynthesis. Although most research focused on increasing reducing power
Yuuma Ishikawa, Maki Kawai-Yamada
doaj   +1 more source

The Synthesis of Poly-L-Lysine-Succinyl-Nadp: An Analogue for Nadp/H

, 1980
Poly-L-lysine-succinyl-NADP, an analogue for nicotinamide adenine dinucleotide phosphate (NADP/H), has been synthesized by linking NADP/H to poly-L-lysine hydrobromide.
S.S. Sofer, W.M. Southard, R.A. Wills
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

NAMPT-mediated salvage synthesis of NAD+ controls morphofunctional changes of macrophages. [PDF]

PLoS ONE, 2014
Functional morphodynamic behavior of differentiated macrophages is strongly controlled by actin cytoskeleton rearrangements, a process in which also metabolic cofactors ATP and NAD(H) (i.e. NAD+ and NADH) and NADP(H) (i.e.
Gerda Venter, Frank T J J Oerlemans, Marieke Willemse, Mietske Wijers, Jack A M Fransen, Bé Wieringa   +5 more
doaj   +1 more source

Induced Fit and Equilibrium Dynamics for High Catalytic Efficiency in Ferredoxin-NADP(H) Reductases

, 2016
Ferredoxin-NADP(H) reductase (FNR) is a FAD-containing protein that catalyzes the reversible transfer of electrons between NADP(H) and ferredoxin or flavodoxin.
Darío H. Paladini (2367400), Eduardo A. Ceccarelli (197230), Matías A. Musumeci (2218000), Néstor Carrillo (2367403)   +3 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source