Results 41 to 50 of about 56,952 (277)

Association of ferredoxin-NADP+ reductase with NADP(H) specificity and oxidation-reduction properties.

Journal of Biological Chemistry, 1986
The equilibrium properties of the NADP+ binding site of ferredoxin-NADP+ reductase (FNR, or Fd-NADP+ reductase) were examined with regard to specificity in binding, and with regard to the oxidation-reduction properties of the FNR.NADP+ complex. With the exception of 3'-NADP+, only adenosine nucleotides with a 2'-adenosyl phosphate bound to Fd-NADP ...
C J, Batie, H, Kamin
openaire   +2 more sources

Genome-wide analysis revealed the stepwise origin and functional diversification of HSDs from lower to higher plant species

Frontiers in Plant Science, 2023
Hydroxysteroid dehydrogenase (HSDs) is an oil-body sterol protein (steroleosin) with an NADP(H) binding domain that belongs to the short-chain dehydrogenase/reductase (SDR) superfamily. There are numerous studies on the characterization of HSDs in plants.
Noor Saleem, Usman Aziz, Muhammad Ali, Xiangling Liu, Khairiah Mubarak Alwutayd, Rana M. Alshegaihi, Gniewko Niedbała, Amr Elkelish, Amr Elkelish, Meng Zhang   +9 more
doaj   +1 more source

In planta study of photosynthesis and photorespiration using NADPH and NADH/NAD+ fluorescent protein sensors

Nature Communications, 2020
NADP(H) and NAD(H) are crucial energy molecules in plant metabolism. Here, via the use of circularly permutated fluorescent protein sensors, the authors demonstrate dynamic changes in NADPH and the NADH/NAD+ ratio during photosynthesis and ...
Shey-Li Lim, Chia Pao Voon, Xiaoqian Guan, Yi Yang, Per Gardeström, Boon Leong Lim   +5 more
doaj   +1 more source

SdrA, an NADP(H)-regenerating enzyme, is crucial for Coxiella burnetii to resist oxidative stress and replicate intracellularly [PDF]

, 2020
Coxiella burnetii, the causative agent of the zoonotic disease Q fever, is a Gram-negative bacterium that replicates inside macrophages within a highly oxidative vacuole.
Newton, HJ, Sansom, FM, Bitew, MA, Hofmann, J, Wawegama, NK, De Souza, DP   +5 more
core   +1 more source

Binding of methimazole and NADP(H) to human FMO3: In vitro and in silico studies [PDF]

International Journal of Biological Macromolecules, 2018
Human flavin-containing monooxygenase isoform 3 (hFMO3) is an important hepatic drug-metabolizing enzyme, catalyzing the monooxygenation of nucleophilic heteroatom-containing xenobiotics. Based on the structure of bacterial FMO, it is proposed that a conserved asparagine is involved in both NADP(H) and substrate binding. In order to explore the role of
Chongliang Gao, Gianluca Catucci, Gianfranco Gilardi, Sheila J. Sadeghi   +3 more
openaire   +2 more sources

Proposed mechanism of FMN-DI catalyzing the hydride transfer between NAD(H) and NADP(H).

, 2016
Proposed mechanism of FMN-DI catalyzing the hydride transfer between NAD(H) and NADP(H).
Fangfang Sun (2410654), Ting Zhang (102583), Jinglin Fu (225092), John Collins (1769020), Scott Huston (2657011), Y.-H. Percival Zhang (28712)   +5 more
core   +1 more source

Short-Term Low Temperature Induces Nitro-Oxidative Stress that Deregulates the NADP-Malic Enzyme Function by Tyrosine Nitration in Arabidopsis thaliana

Antioxidants, 2019
Low temperature (LT) negatively affects plant growth and development via the alteration of the metabolism of reactive oxygen and nitrogen species (ROS and RNS).
Juan C. Begara-Morales, Beatriz Sánchez-Calvo, María V. Gómez-Rodríguez, Mounira Chaki, Raquel Valderrama, Capilla Mata-Pérez, Javier López-Jaramillo, Francisco J. Corpas, Juan B. Barroso   +8 more
doaj   +1 more source

Change in Cofactor Specificity of Oxidoreductases by Adaptive Evolution of an Escherichia coli NADPH-Auxotrophic Strain

mBio, 2021
The nicotinamide cofactor specificity of enzymes plays a key role in regulating metabolic processes and attaining cellular homeostasis. Multiple studies have used enzyme engineering tools or a directed evolution approach to switch the cofactor preference
Madeleine Bouzon, Volker Döring, Ivan Dubois, Anne Berger, Gabriele M. M. Stoffel, Liliana Calzadiaz Ramirez, Sophia N. Meyer, Marion Fouré, David Roche, Alain Perret, Tobias J. Erb, Arren Bar-Even, Steffen N. Lindner   +12 more
doaj   +1 more source

Induced Fit and Equilibrium Dynamics for High Catalytic Efficiency in Ferredoxin-NADP(H) Reductases

, 2016
Ferredoxin-NADP(H) reductase (FNR) is a FAD-containing protein that catalyzes the reversible transfer of electrons between NADP(H) and ferredoxin or flavodoxin.
Darío H. Paladini (2367400), Eduardo A. Ceccarelli (197230), Matías A. Musumeci (2218000), Néstor Carrillo (2367403)   +3 more
core   +1 more source

Dynamic and Static Regulation of Nicotinamide Adenine Dinucleotide Phosphate: Strategies, Challenges, and Future Directions in Metabolic Engineering

Molecules
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is a crucial cofactor in metabolic networks. The efficient regeneration of NADPH is one of the limiting factors for productivity in biotransformation processes.
Nana Ding, Zenan Yuan, Lei Sun, Lianghong Yin   +3 more
doaj   +1 more source