Results 81 to 90 of about 56,952 (277)

Decarboxylation mechanisms of C4 photosynthesis in Saccharum spp.: increased PEPCK activity under water-limiting conditions

BMC Plant Biology, 2019
Background C4 plants have been classified into three subtypes based on the enzymes used to decarboxylate C4 acids in the bundle sheath cells (NADP-ME, NAD-ME and PEPCK pathways).
Viviane Cacefo, Alessandra Ferreira Ribas, Rafael Rebes Zilliani, Daniel Moreira Neris, Douglas Silva Domingues, Adriana Lima Moro, Luiz Gonzaga Esteves Vieira   +6 more
doaj   +1 more source

Properties of the apo-form of the NADP(H)-binding domain III of proton-pumping Escherichia coli transhydrogenase: implications for the reaction mechanism of the intact enzyme

, 2003
Proton-translocating nicotinamide nucleotide transhydrogenases contain an NAD(H)-binding domain (dI), an NADP(H)-binding domain (dIII) and a membrane domain (dII) with the proton channel. Separately expressed and isolated dIII contains tightly bound NADP(
Jenny Karlsson, Althage, Magnus,, Althage, Magnus, Pedersen, Anders,, Karlsson, J,, Pedersen, Anders, Jan Rydström, Anders Pedersen, Karlsson, Jenny, Magnus Althage, Rydström, Jan,, Rydström, Jan   +11 more
core   +1 more source

Quantifying Interactions Within the NADP(H) Enzyme Network in Drosophila melanogaster [PDF]

Genetics, 2009
Abstract In this report, we use synthetic, activity-variant alleles in Drosophila melanogaster to quantify interactions across the enzyme network that reduces nicotinamide adenine dinucleotide phosphate (NADP) to NADPH. We examine the effects of large-scale variation in isocitrate dehydrogenase (IDH) or glucose-6-phosphate dehydrogenase (
Thomas J S, Merritt, Caitlin, Kuczynski, Efe, Sezgin, Chen-Tseh, Zhu, Seiji, Kumagai, Walter F, Eanes   +5 more
openaire   +2 more sources

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Conformational Change in the NADP(H) Binding Domain of Transhydrogenase Defines Four States^†,‡

, 2016
Proton-translocating transhydrogenase (TH) couples direct and stereospecific hydride transfer between NAD(H) and NADP(H), bound to soluble domains dI and dIII, respectively, to proton translocation across a membrane bound domain, dII. The reaction occurs
Vidyasankar Sundaresan (2731615), Mutsuo Yamaguchi (2731618), Justin Chartron (2497807), C. David Stout (213073)   +3 more
core   +1 more source

Tumor Microenvironment‐Responsive Nanoreactor Induces Disulfidptosis in Pancreatic Cancer via Metabolic Interference and Redox Catalysis

Advanced Science, EarlyView.
Schematic illustration of a tumor microenvironment‐responsive nanoreactor for imaging‐guided induction of disulfidptosis in pancreatic cancer via metabolic interference and redox catalysis. (A) Stepwise fabrication of Pht@HMnO2‐HA, including MnO2 growth on a SiO2 template, template removal to form hollow mesoporous MnO2, Pht loading, and subsequent ...
Rui Fu, Qing Li, Guanzhong Zhao, Qingyan Gao, Huantong Chen, Khemayanto Hidayat, Jiaying Xu, Liqiang Qin, Chunhong Hu, Yu Chong, Su Hu   +10 more
wiley   +1 more source

Structure-guided engineering of the coenzyme specificity of Pseudomonas fluorescens mannitol 2-dehydrogenase to enable efficient utilization of NAD(H) and NADP(H)

, 2008
The structure of Pseudomonas fluorescens mannitol 2-dehydrogenase with bound NAD+ leads to the suggestion that the carboxylate group of Asp69 forms a bifurcated hydrogen bond with the 2′ and 3′ hydroxyl groups of the adenosine of NAD+ and contributes to ...
Mario Klimacek, Bubner, Patricia, Patricia Bubner, Bernd Nidetzky, Klimacek, Mario, Nidetzky, Bernd   +5 more
core   +1 more source

Elektroenzymatische CO2‐Fixierung

Angewandte Chemie, EarlyView.
Die elektroenzymatische CO2‐Fixierung ermöglicht eine energieeffiziente, hochselektive Synthese komplexer Moleküle. Um ihr volles Potenzial auszuschöpfen, ist ein grundlegendes Verständnis von elektrodengekoppelten Reduktasen und Carboxylasen erforderlich.
Leonardo Castañeda‐Losada, Michael Richter, Christophe Léger, Vincent Fourmond, Nicolas Plumeré   +4 more
wiley   +1 more source

NADP- und NAD-spezifische Isocitrat-Dehydrogenase in Hydrogenomonas eutropha Stamm H 16.

, 1972
Aus einem Rohextrakt von Hydrogenomonas eutropha Stamm H16-Fructosezellen wurden eine NADP- und eine NAD-spezifische Isocitrat-Dehydrogenase teilweise gereinigt und getrennt. Beide Enzyme sind in ihrer Affinität zum Isocitrat und zu NADP bzw.
Schlegel, H.G., Glaeser, H.
core   +1 more source

Electroenzymatic CO2 Fixation

Angewandte Chemie International Edition, EarlyView.
Electroenzymatic CO2 fixation enables energy‐efficient, highly selective synthesis of complex molecules. Unlocking its full potential requires fundamental understanding of electrode‐coupled reductases and carboxylases. This review critically discusses available enzymes, product scope, and key thermodynamic and kinetic considerations, highlighting ...
Leonardo Castañeda‐Losada, Michael Richter, Christophe Léger, Vincent Fourmond, Nicolas Plumeré   +4 more
wiley   +1 more source