Results 1 to 10 of about 183,802 (357)
ROS Signaling and NADPH Oxidase in Red Algae [PDF]
AntioxidantsWe explore the diverse roles of reactive oxygen species (ROS) and NADPH oxidases in red algae, focusing on their involvement in fertilization, wound repair, stress adaptation, and development.
Gwang-Hoon Kim +2 more
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A role for NADPH oxidase in antigen presentation [PDF]
Frontiers in Immunology, 2013 The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase expressed in phagocytes is a multi-subunit enzyme complex that generates superoxide (O2.-).
Gail J Gardiner +5 more
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NoxO1 Determines the Level of ROS Formation by the Nox1-Centered NADPH Oxidase [PDF]
AntioxidantsThe Nox1-centered NADPH oxidase complex facilitates the transfer of electrons from intracellular NADPH across the cell membrane to extracellular molecular oxygen, resulting in the formation of superoxide.
Dana Maureen Hebchen +3 more
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NADPH Oxidase and Neurodegeneration [PDF]
Current Neuropharmacology, 2012 NADPH oxidase (Nox) is a unique, multi-protein, electron transport system that produces large amounts of superoxide via the reduction of molecular oxygen. Nox-derived reactive oxygen species (ROS) are known to be involved in a variety of physiological processes, including host defense and signal transduction.
Marina S. Hernandes, Luiz R.G. Britto
openaire +2 more sources
NADPH oxidase limits innate immune responses in the lungs in mice. [PDF]
PLoS ONE, 2010 Chronic granulomatous disease (CGD), an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide anion and downstream reactive oxidant intermediates (ROIs), is characterized by recurrent bacterial and fungal ...
Brahm H Segal +20 more
doaj +1 more source
Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice. [PDF]
PLoS ONE, 2013 The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses.
Heidi E Godoy +10 more
doaj +1 more source
Antioxidants, 2021 Alzheimer’s disease (AD) is one of the main human dementias around the world which is constantly increasing every year due to several factors (age, genetics, environment, etc.) and there are no prevention or treatment options to cure it.
Leticia Guadalupe Fragoso-Morales +2 more
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NADPH Oxidases and Their Role in Atherosclerosis [PDF]
Biomedicines, 2020 The current view on atherosclerosis positions it as a multifactorial disorder that results from the interplay between lipid metabolism disturbances and inflammatory processes. Oxidative stress is proven to be one of the initiating factors in atherosclerosis development, being implicated both in the inflammatory response and in atherogenic modifications
Anastasia V. Poznyak +5 more
openaire +4 more sources
NADPH Oxidases in Pain Processing
Antioxidants, 2022 Inflammation or injury to the somatosensory nervous system may result in chronic pain conditions, which affect millions of people and often cause major health problems. Emerging lines of evidence indicate that reactive oxygen species (ROS), such as superoxide anion or hydrogen peroxide, are produced in the nociceptive system during chronic inflammatory
Wiebke Kallenborn-Gerhardt +2 more
openaire +4 more sources
Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense. [PDF]
PLoS ONE, 2011 NADPH oxidase is a crucial enzyme in mediating antimicrobial host defense and in regulating inflammation. Patients with chronic granulomatous disease, an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive ...
R Robert Vethanayagam +10 more
doaj +1 more source