Results 121 to 130 of about 95,385 (310)

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

Synthesis, Characterization, Biological Evaluation, DFT Calculations, and Molecular Docking Study of Transition Metal Complexes Derived From a Schiff Base Ligand

Chemistry &Biodiversity, EarlyView.
ABSTRACT The escalating global challenge of antibiotic resistance amid rising oxidative stress emphasizes the critical necessity for innovative antimicrobial strategies. This study, reported synthesis of Schiff base ligand, (Z)‐2‐[(4‐nitrobenzylidene)amino]phenol (HL), derived from condensation between 2‐aminophenol and 4‐nitrobenzaldehyde, and it Co ...
Ibrahim Waziri, Olaide O. Wahab, Grema A. Mala, Musa B. Ismaila, Usman Umaru, Mostafa S. Abd El‐Maksoud, Ibrahim M. Wakil, Tunde L. Yusuf   +7 more
wiley   +1 more source

Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P-450 reductase and xanthine oxidase.

, 1984
Shengze Pan, Paul A. Andrews, Constance J. Glover, N R Bachur   +3 more
openalex   +1 more source

Selective Oxidation of α,β‐Unsaturated Alcohols With Lyophilisates of Bjerkandera adusta

Chemistry &Biodiversity, EarlyView.
ABSTRACT The biocatalytic aerobic production of (E)‐2‐allylic aldehydes from their corresponding alcohols using lyophilisates of the basidiomycetous fungus Bjerkandera adusta is reported. The addition of small amounts of organic solvents to the reaction media increased the reaction and substrate conversion rates, allowing for to produce (E)‐aldehydes ...
Letizia Calza, Valeriia Nikitenkova, Wendell Albuquerque, Holger Zorn, Tatyana Zhuk   +4 more
wiley   +1 more source

CARDIOVASCULAR BIOMARKERS, TYG INDEX AND TG/HDL-C RATIO IN SUBCLINICAL HYPOTHYROIDISM PATIENTS

Science Journal of University of Zakho
Subclinical hypothyroidism (SCH) is characterized by exhibiting a normal value of free thyroxine (T4) and excessive blood thyroid-stimulating hormone (TSH) concentration.
Barhav Abdullah, Sherwan Salih
doaj   +1 more source

X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox [PDF]

, 1993
Stephen Porter, M. Parkar, RJ Levinsky, MK Collins, Christine Kinnon   +4 more
openalex   +1 more source

The Predictive Value of Quantitative Flow Ratio and Its Derived Angiographic Microvascular Resistance for Restenosis Following Drug‐Coated Balloon Angioplasty

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Initially, drug‐coated balloon (DCB) angioplasty was primarily employed for in‐stent restenosis (ISR) treatment. Over time, its indications have broadened to include de novo small‐vessel lesions and bifurcation lesions. However, there is a lack of effective strategies to reduce restenosis rates post‐DCB angioplasty.
Chenhang Wang, Li Chen, Xiaoyong Xu
wiley   +1 more source

Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.

, 1985
Daniel L. Simmons, P.A. Lalley, Charles B. Kasper   +2 more
openalex   +1 more source

Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers [PDF]

, 1994
Martin de Boer, PM Hilarius-Stokman, JP Hossle, AJ Verhoeven, Nadja Graf, Richard T. Kenney, Reinhard Seger, Dirk Roos   +7 more
openalex   +1 more source

A Mechanochemical Route for the Synthesis of Diphenyleneiodonium Salts and the Estimation of Their Relative Solid‐State Reactivities

Chemistry–Methods, EarlyView.
An efficient mechanochemical route for diphenyleneiodonium (DPI) salt synthesis is reported which offers a sustainable and solvent‐free alternative. The solid‐state reactivities of the reported DPI salts were also assessed with the help of morphology predictions and Hirshfeld surface analysis computations to understand the effect of crystal morphology,
Ipsha Shruti, Tejender S. Thakur
wiley   +1 more source