Results 11 to 20 of about 95,385 (310)
NADPH Oxidase and Neurodegeneration [PDF]
Current Neuropharmacology, 2012 NADPH oxidase (Nox) is a unique, multi-protein, electron transport system that produces large amounts of superoxide via the reduction of molecular oxygen. Nox-derived reactive oxygen species (ROS) are known to be involved in a variety of physiological processes, including host defense and signal transduction.
Marina S. Hernandes, Luiz R.G. Britto
openaire +2 more sources
NADPH Oxidases and Their Role in Atherosclerosis [PDF]
Biomedicines, 2020 The current view on atherosclerosis positions it as a multifactorial disorder that results from the interplay between lipid metabolism disturbances and inflammatory processes. Oxidative stress is proven to be one of the initiating factors in atherosclerosis development, being implicated both in the inflammatory response and in atherogenic modifications
Anastasia V. Poznyak +5 more
openaire +4 more sources
NADPH Oxidases in Pain Processing
Antioxidants, 2022 Inflammation or injury to the somatosensory nervous system may result in chronic pain conditions, which affect millions of people and often cause major health problems. Emerging lines of evidence indicate that reactive oxygen species (ROS), such as superoxide anion or hydrogen peroxide, are produced in the nociceptive system during chronic inflammatory
Wiebke Kallenborn-Gerhardt +2 more
openaire +4 more sources
Regulation of Plant NADPH Oxidase [PDF]
Plant Signaling & Behavior, 2007 The production of Reactive Oxygen Species (ROS) is one of the key events occurring during the response of plants to environmental changes, and contributing to establish adaptive signaling pathways. A plasma membrane bound NADPH oxidase enzyme has been evidenced as the ROS producing system in various plant-microorganisms interactions.
Elmayan, Taline, Simon-Plas, Françoise
openaire +4 more sources
NADPH Oxidases in Vascular Pathology [PDF]
Antioxidants & Redox Signaling, 2014 Reactive oxygen species (ROS) play a critical role in vascular disease. While there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases play a central role. They are a source of "kindling radicals," which affect other enzymes, such as nitric oxide synthase endothelial nitric oxide synthase or xanthine oxidase.
Tomasz J. Guzik +3 more
openaire +4 more sources
Redox modulation of FAK controls melanoma survival--role of NOX4. [PDF]
PLoS ONE, 2014 Studies have demonstrated that reactive oxygen species (ROS) generated by NADPH oxidase are essential for melanoma proliferation and survival. However, the mechanisms by which NADPH oxidase regulates these effects are still unclear.
Cristiane Ribeiro-Pereira +5 more
doaj +1 more source
Acta Societatis Botanicorum Poloniae, 2017 Cadmium-induced oxidative burst is partially mediated by NADPH oxidase. The aim of the present research was to evaluate the role of NADPH oxidase in soybeans’ response to short-term cadmium stress.
Jagna Chmielowska-Bąk +6 more
doaj +1 more source
Effects of Iodonium Analogs on Nadph Oxidase 1 in Human Colon Cancer Cells
Antioxidants, 2021 Recent studies suggest that of the molecules postulated to function as inhibitors of the NADPH oxidase family of enzymes iodonium analogs known to broadly interfere with flavin dehydrogenase function demonstrate mechanistic validity as NADPH oxidase ...
Krishnendu K. Roy +2 more
doaj +1 more source
Phosphatidylinositol 3-kinase plays a vital role in regulation of rice seed vigor via altering NADPH oxidase activity. [PDF]
PLoS ONE, 2012 Phosphatidylinositol 3-kinase (PI3K) has been reported to be important in normal plant growth and stress responses. In this study, it was verified that PI3K played a vital role in rice seed germination through regulating NADPH oxidase activity ...
Jian Liu, Jun Zhou, Da Xing
doaj +1 more source
Redox Biology, 2017 Histone deacetylase 6 (HDAC6) likely is important in inflammatory diseases. However, how HDAC6 exerts its effect on inflammatory processes remains unclear.
Gi Soo Youn +4 more
doaj +1 more source