The Role of NADPH Oxidase in Neuronal Death and Neurogenesis after Acute Neurological Disorders
Antioxidants, 2021 Oxidative stress is a well-known common pathological process involved in mediating acute neurological injuries, such as stroke, traumatic brain injury, epilepsy, and hypoglycemia-related neuronal injury.
Song Hee Lee +4 more
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NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin system [PDF]
, 2003 Objective: We previously reported that intrauterine undernutrition increased the oxidative stress by decreasing superoxide dismutase activity. in the present study, we tested whether NADPH oxidase, xanthine oxidase, cyclooxygenase or nitric oxide ...
Akamine, E. H. +6 more
core +1 more source
p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels. [PDF]
, 2016 BACKGROUND: The NADPH oxidase, by generating reactive oxygen species, is involved in the pathophysiology of many cardiovascular diseases and represents a therapeutic target for the development of novel drugs.
Brooks, G +6 more
core +1 more source
Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating JNK and NADPH oxidase-dependent generation of reactive oxygen species. [PDF]
PLoS ONE, 2012 Khz is a compound derived from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia that inhibits the growth of cancer cells. The results of the present study show that Khz induced apoptosis preferentially in transformed cells and had only ...
Tae Hwan Kim +4 more
doaj +1 more source
Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors [PDF]
, 2001 Airway neuroepithelial bodies sense changes in inspired O2, whereas arterial O2 levels are monitored primarily by the carotid body. Both respond to hypoxia by initiating corrective cardiorespiratory reflexes, thereby optimising gas exchange in the face ...
Kemp, P.J., Peers, C.
core +4 more sources
Molecular Plant-Microbe Interactions, 2001 Among plant defense responses to pathogen attack, the release of active oxygen species (AOS), termed the oxidative burst, may affect the attacking pathogen and the host plant cells at the infection site, thereby limiting the spread of the pathogen ...
Tim Xing +3 more
doaj +1 more source
Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung [PDF]
, 2014 Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. It has recently been shown to function as a negative regulator of β2-integrin-dependent neutrophil recruitment to the lung following exposure to lipopolysaccharide (LPS).
Anderson +23 more
core +3 more sources
Journal of Ophthalmology, 2010 Objectives. Using apocynin (inhibitor of NADPH oxidase), and Mitoquinol 10 nitrate (MitoQ; mitochondrial-targeted antioxidant), we addressed the importance of mitochondria versus NADPH oxidase-derived ROS in glucose-induced apoptosis of pericytes ...
Nik M. Mustapha +3 more
doaj +1 more source
Redox Biology, 2017 Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown.
Varun Chandrashekaran +9 more
doaj +1 more source
NADPH Oxidases in Aortic Aneurysms
Antioxidants, 2022 Abdominal aortic aneurysms (AAAs) are a progressive dilation of the infrarenal aorta and are characterized by inflammatory cell infiltration, smooth muscle cell migration and proliferation, and degradation of the extracellular matrix. Oxidative stress and the production of reactive oxygen species (ROS) have been shown to play roles in inflammatory cell
openaire +3 more sources