Results 41 to 50 of about 95,385 (310)
Molecules, 2023 Disruption of apoptosis leads to cancer cell progression; thus, anticancer agents target apoptosis of cancer cells. Reactive oxygen species (ROS) induce apoptosis by activating caspases and caspase-dependent DNase, leading to DNA fragmentation.
Ju Won Eom, Joo Weon Lim, Hyeyoung Kim
doaj +1 more source
NADPH Oxidase Deficiency: A Multisystem Approach [PDF]
Oxidative Medicine and Cellular Longevity, 2017 The immune system is a complex system able to recognize a wide variety of host agents, through different biological processes. For example, controlled changes in the redox state are able to start different pathways in immune cells and are involved in the killing of microbes.
Giuliana Giardino +9 more
openaire +4 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea. [PDF]
PLoS ONE, 2011 In rodents, exposure to intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), is associated with neurobehavioral impairments, increased apoptosis in the hippocampus and cortex, as well as increased oxidant stress and inflammation ...
Deepti Nair +4 more
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Clarity on the Isoform-Specific Roles of NADPH Oxidases and NADPH Oxidase-4 in Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016 Atherosclerosis is a complex disease that remains a leading cause of death and disability. The formation of vascular plaques arises from the interaction of dyslipidemia with the altered function of blood vessels and immune cells. The exact cause of atherosclerosis is not known, but from the 1950s onward, oxidative modifications of lipids and proteins ...
David Fulton, Scott A. Barman
openaire +3 more sources
Biosupercapacitors for Human‐Powered Electronics
Advanced Functional Materials, EarlyView.Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim +7 more
wiley +1 more source
ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing
Advanced Healthcare Materials, EarlyView.A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha +4 more
wiley +1 more source
PLoS ONE, 2016 RationaleObesity is often associated with a state of oxidative stress and increased lipid deposition in the heart. More importantly, obesity increases lipid influx into the heart and induces excessive production of reactive oxygen species (ROS) leading ...
Mohamed Gharib +3 more
doaj +1 more source
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun +9 more
wiley +1 more source
Role of Resveratrol on the Effect of Resistin in Rabbit Corpus Cavernosum
Journal of Urological Surgery, 2020 Objective:Resistin is an important factor in the pathogenesis of obesity-induced insulin resistance and endothelial dysfunction-mediated cardiovascular system diseases.
Türkan Güngör +4 more
doaj +1 more source