Results 161 to 170 of about 85,856,906 (279)

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

GLX351322, a Novel NADPH Oxidase 4 Inhibitor, Attenuates TMJ Osteoarthritis by Inhibiting the ROS/MAPK/NF-κB Signaling Pathways. [PDF]

Oxid Med Cell Longev, 2023
Zhen J, Chen X, Mao Y, Xie X, Chen X, Xu W, Zhang S.   +6 more
europepmc   +1 more source

Modulation of Arachidonic Acid Metabolism by Pinoresinol Diglucoside Ameliorates Osteogenic Dysfunction via Coordinated NF‐κB Suppression and GSK3β/β‐Catenin Activation in Diabetic Osteoporosis

Phytotherapy Research, EarlyView.
ABSTRACT Diabetic osteoporosis (DOP) is characterized by chronic low‐grade inflammation and impaired bone formation. Pinoresinol diglucoside (PDG), a bioactive compound derived from Eucommia ulmoides Oliv., has shown therapeutic potential in metabolic bone disorders; however, its direct molecular targets and integrated mechanisms remain unclear.
Wenqi Jin, Yujing Tan, Lei Zhang, Weigeng She, Yunhang Chu, Xuenan Chen, Shuai Zhang, Liwei Sun   +7 more
wiley   +1 more source

Studies of NADPH oxidase composition and function by monoclonal antibodies

, 1989
The composition of NADPH oxidase is investigated by the use of antibodies raised against its ...
BERTON, Giorgio, DUSI, Stefano, BAZZONI, Flavia, BELLAVITE, Paolo   +3 more
core   +1 more source

NADPH-oxidase 4 gene over-expression in peripheral blood lymphocytes of the schizophrenia patients. [PDF]

PLoS One, 2022
Ershova ES, Shmarina GV, Martynov AV, Zakharova NV, Veiko RV, Umriukhin PE, Kostyuk GP, Kutsev SI, Veiko NN, Kostyuk SV.   +9 more
europepmc   +1 more source

Multifunctional Nanoreactor Based on Catalyst Surface Engineering Combines pH‐Adaptive Catalysis With Tumor Microenvironment Modulation for Synergistic Chemodynamic‐Chemotherapy

Small, EarlyView.
A folate‐targeted Fe2O3@MoS2‐Pt/FA nanoreactor creates a localized acidic catalytic interface while simultaneously elevating intracellular H2O2 and consuming GSH. This dual regulation of reaction conditions and substrate availability markedly enhances Fenton‐driven chemodynamic therapy and synergistic chemotherapy for efficient tumor eradication ...
Yuchen Liu, Shan Lin, Pengyuan Song, Xianan Li, Jingwen Wang, Yang Zhang, Mingli Cai, Kang Fu, Ziyue Xu, Qianqian Zhao, Long Zhang, Jie Shen, Shibo Wang, Xiangdong Kong, Pu Chen   +14 more
wiley   +1 more source

NADPH Oxidase 4 (NOX4) in Cancer: Linking Redox Signals to Oncogenic Metabolic Adaptation. [PDF]

Int J Mol Sci, 2022
Szanto I.
europepmc   +1 more source

Beyond Removal Efficiency: Environmental Risk Assessment of Tartrazine Degradation via ZnO and TiO2 Nanoparticles in Mussels

Environmental Toxicology, EarlyView.
ABSTRACT Tartrazine (TZ) is a widely used synthetic azo dye with high aqueous stability, resulting in persistence in wastewater. Photoreactive nanomaterials, principally zinc oxide (ZnO) and titanium dioxide (TiO2) nanoparticles (NPs), are frequently employed for dye removal under light‐exposed conditions; nevertheless, their ecotoxicological ...
İrem Can, Ezgi Can Güzel, Volkan Saritunç, Selin Ertürk Gürkan   +3 more
wiley   +1 more source

MicroRNA-454 modulates the oxidative stress and neuronal apoptosis after cerebral ischemia/reperfusion injury via targeting NADPH oxidase 4 (NOX4). [PDF]

J Biochem Mol Toxicol, 2022
Zhang T, Han H, Zhou Y, Liu Z, Ma T, Cao X.   +5 more
europepmc   +1 more source