Results 121 to 130 of about 297,991 (354)
Diphenyleneiodonium, an inhibitor of NOXes and DUOXes, is also an iodide-specific transporter
NADPH oxidases (NOXes) and dual oxidases (DUOXes) generate O2.− and H2O2. Diphenyleneiodonium (DPI) inhibits the activity of these enzymes and is often used as a specific inhibitor.
C. Massart+5 more
doaj +1 more source
Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors. [PDF]
Oxidative stress-related diseases underlie many if not all of the major leading causes of death in United States and the Western World. Thus, enormous interest from both academia and pharmaceutical industry has been placed on the development of agents ...
Cifuentes-Pagano, ME+2 more
core +1 more source
The Importance of NADPH Oxidases and Redox Signaling in Angiogenesis
Eukaryotic cells have to cope with the constant generation of reactive oxygen species (ROS). Although the excessive production of ROS might be deleterious for cell biology, there is a plethora of evidence showing that moderate levels of ROS are important
Rodrigo Prieto-Bermejo+1 more
semanticscholar +1 more source
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou+3 more
wiley +1 more source
Diabetic Cardiovascular Disease Induced by Oxidative Stress. [PDF]
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications, including coronary artery disease (CAD), cardiac hypertrophy, and heart failure
Adam, Matti+9 more
core +2 more sources
Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou+7 more
wiley +1 more source
Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress [PDF]
When cellular reducing enzymes fail to shield the cell from increased amounts of reactive oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and proteins are damaged and cellular transcription networks are activated.
Abdulkadir+99 more
core +2 more sources
Many plants accumulate proline, a compatible osmolyte, in response to various environmental stresses such as water deficit and salinity. In some stress responses, plants generate hydrogen peroxide (H2 O2 ) that mediates numerous physiological and ...
Kilani Ben Rejeb+8 more
semanticscholar +1 more source
Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley +1 more source
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek+5 more
wiley +1 more source