Results 111 to 120 of about 25,108 (267)
Arthritis &Rheumatology, EarlyView.Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu +12 more
wiley +1 more source
Supplementary Figure 2 from NADPH Oxidases as Therapeutic Targets in Chronic Myelogenous Leukemia
, 2014 PDF file - 108KB, Supplementary figure 2. Analysis of the interaction of NADPH oxidases inhibitors and BCR-ABL in bone marrow cells from healthy donors.
Sara Gutiérrez-Herrero (6105209) +11 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo +9 more
wiley +1 more source
Communicative & Integrative Biology, 2016 Reactive oxygen species (ROS) play an important role in causing neuronal death in a number of neurological disorders. We recently reported that ROS serve as a signal to activate neuronal apoptosis and axonal degeneration by activating ZNRF1 (zinc- and ...
Shuji Wakatsuki, Toshiyuki Araki
doaj +1 more source
Phylogeny and Expression of NADPH Oxidases during Symbiotic Nodule Formation
Agriculture, 2018 The mutualistic interaction between gram-negative soil bacteria and the roots of legumes leads to the establishment of nodules, where atmospheric nitrogen is fixed. Nodulation is a multistep process with numerous essential players.
Jesús Montiel +2 more
doaj +1 more source
Supplementary Figure 5 from NADPH Oxidases as Therapeutic Targets in Chronic Myelogenous Leukemia
, 2014 PDF file - 340KB, Supplementary figure 5. Combination of NADPH oxidases and BCR-ABL inhibitors progressively increases the proportion of sub-G1 phase cells.
Sara Gutiérrez-Herrero (6105209) +11 more
core +1 more source
Circulation Research, 2009 Over the last decade, the NADPH oxidases have been recognized as an important source of reactive oxygen species (ROS) involved in both normal physiologic redox-dependent processes, and in the generation of oxidative stress, with a role in the development of cardiovascular disease.
openaire +2 more sources
British Journal of Clinical Pharmacology, EarlyView.SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić +7 more
wiley +1 more source
Overactivation of NADPH Oxidases – A pathophysiological correlate in Multiple Sclerosis?
, 2017 In der Multiplen Sklerose sind Monozyten/Makrophagen als pathogenetisch relevante Immunzellen umfangreich beschrieben. Möglichweise leisten NADPH Oxidasen einen Beitrag zum Krankheitsgeschehen und dem Untergang von Nervenzellen, wobei deren Rolle bislang
Pohlan, Julian
core +1 more source
BMEMat, EarlyView.The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng +10 more
wiley +1 more source