Results 101 to 110 of about 42,623 (284)
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources
Diphenyleneiodonium, an inhibitor of NOXes and DUOXes, is also an iodide-specific transporter
NADPH oxidases (NOXes) and dual oxidases (DUOXes) generate O2.− and H2O2. Diphenyleneiodonium (DPI) inhibits the activity of these enzymes and is often used as a specific inhibitor.
C. Massart +5 more
doaj +1 more source
Teaching the Basics of Reactive Oxygen Species and their Relevance to Cancer Biology: Mitochondrial Reactive Oxygen Species Detection, Redox Signaling, and Targeted Therapies [PDF]
Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes are possibly the most ...
Bennett, Brian +5 more
core +1 more source
Anti-inflammatory activity of Chios mastic gum is associated with inhibition of TNF-alpha induced oxidative stress [PDF]
Background Gum of Chios mastic (Pistacia lentiscus var. chia) is a natural antimicrobial agent that has found extensive use in pharmaceutical products and as a nutritional supplement.
Angelike Triantafyllou +5 more
core +2 more sources
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang +8 more
wiley +1 more source
Relationship between NOX4 level and angiotensin II signaling in Gitelman's syndrome. Implications with hypertension [PDF]
Recent evidence showed that endogenous nicotinamide adenine dinucleotide phosphate-oxidase 4 (NOX4) may exert a protective role on the cardiovascular system inducing vasodilation, reduction of blood pressure, and anti-proliferative actions.
Calò, Lorenzo A +5 more
core
c-Src inhibition improves cardiovascular function but not remodeling or fibrosis in Ang II-induced hypertension [PDF]
c-Src plays an important role in angiotensin II (Ang II) signaling. Whether this member of the Src family kinases is involved in the development of Ang II–induced hypertension and associated cardiovascular damage in vivo remains unknown. Here, we studied
Antunes, Tayze T. +6 more
core +1 more source
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Glucose-6-phosphate dehydrogenase (G6PDH or G6PD) is the key regulatory enzyme in the oxidative pentose phosphate pathway (OPPP). The cytosolic isoforms including G6PD5 and G6PD6 account for the major part of the G6PD total activity in plant cells. Here,
Lei Yang +9 more
doaj +1 more source
Potential role of NADPH-oxidase in early steps of lead-induced oxidative burst in Vicia faba roots [PDF]
The mechanism of oxidative burst induced by lead in Vicia faba excised roots was investigated by luminol-dependent chemiluminescence. Results showed that lead triggered a rapid and dose-dependent increase in chemiluminescence production.
Cecchi, Marie +5 more
core +3 more sources

