Results 101 to 110 of about 74,065 (268)
Natural compounds as modulators of NADPH oxidases. [PDF]
, 2013 Reactive oxygen species (ROS) are cellular signals generated ubiquitously by all mammalian cells, but their relative unbalance triggers also diseases through intracellular damage to DNA, RNA, proteins, and lipids.
MARALDI, Tullia
core +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
AGING MEDICINE, EarlyView.Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
NADPH oxidases in traumatic brain injury – Promising therapeutic targets?
Redox Biology, 2018 Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Despite intense investigation, no neuroprotective agents for TBI have yet translated to the clinic.
Merry W. Ma +4 more
doaj +1 more source
Engineering the substrate specificity of galactose oxidase [PDF]
, 2013 Biocatalysis, the use of enzymes to catalyse the generation of specific chemicals, has a number of advantages including high specificity, lower energy requirements and greater sustainability over an equivalent chemical process.
Chappell, Lucy
core +3 more sources
Enzymatic Assays of NADH- and NADPH-dependent Oxidases from the Beef Liver Proteome.
, 2015 The functional landscape of beef NADH (top panel) and NADPH (bottom panel) dependent oxidases from were shown as a proof of principle of the PEP technology.
Ruqiang Liang (713132) +3 more
core +1 more source
NADPH oxidase‐derived reactive oxygen species: Dosis facit venenum
Experimental Physiology, 2019 New Findings What is the topic of this review? Within this review, the role of reactive oxygen species in cellular homeostasis, physiology and pathophysiology is discussed. What advances does it highlight? The review provides new concepts of how reactive
Katrin Schröder
doaj +1 more source
Caracterização química e atividade de ulvanas na indução de respostas oxidativas associadas ao controle de Alternaria brassicicola e Colletotrichum higginsianum em Arabidopsis thaliana [PDF]
, 2014 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Recursos Genéticos Vegetais, Florianópolis, 2014.Atualmente, a busca por métodos alternativos no controle de doenças de plantas vem ...
Freitas, Mateus Brusco de
core
NADPH oxidase in human lung fibroblasts
Journal of Biomedical Science, 2004 Reactive oxygen species produced by NADPH oxidase appear to play a role in the response of human lung fibroblast cells to rhinovirus infection. The purpose of the following studies was to characterize the NADPH oxidase components in these cells, to examine the effect of rhinovirus challenge on the expression of these proteins, and to confirm previous ...
Gursev S, Dhaunsi +3 more
openaire +2 more sources
Expression and modulation of an NADPH oxidase in mammalian astrocytes [PDF]
, 2005 Amyloid β peptides generate oxidative stress in hippocampal astrocytes through a mechanism sensitive to inhibitors of the NADPH oxidase [diphenylene iodonium (DPI) and apocynin].
Abramov, A.Y. +5 more
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Arthritis &Rheumatology, EarlyView.Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo +9 more
wiley +1 more source