Results 121 to 130 of about 74,065 (268)
This study developed a fucoside‐targeted gold nanocluster probe that enables early NIR‐II imaging and multi‐mechanistic therapy for acute kidney injury, effectively mitigating oxidative stress, modulating inflammatory responses, and inhibiting ferroptosis to improve renal outcomes. Abstract Acute kidney injury (AKI) remains a life‐threatening condition
Ping Zhang +7 more
wiley +1 more source
This short review article summarizes what is known clinically and biochemically about the seven human NADPH oxidases. Emphasis is put on the connection between mutations in the catalytic and regulatory subunits of Nox2, the phagocyte defense enzyme, with
Breitenbach, Michael +8 more
core +1 more source
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino +7 more
wiley +1 more source
Summary of the proposed activation of Nox-2 and Nox-4 NADPH oxidases in the kidney.
The figure shows various cytosolic and membrane components of NADPH oxidase subunits getting activated via Renin/angiotensin receptor-2 activation of the NADPH-oxidases during the development of hyperoxaluria, resulting in increased production of ...
Ammon B. Peck (44268) +4 more
core +1 more source
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley +1 more source
The role of dual oxidases in physiology and cancer
NOX/DUOX enzymes are transmembrane proteins that carry electrons through biological membranes generating reactive oxygen species. The NOX family is composed of seven members, which are NOX1 to NOX5 and DUOX1 and 2.
Caroline Coelho de Faria +1 more
doaj +1 more source
Inhibition of chickpea seedling copper amine oxidases by tetraethylenepentamine [PDF]
Copper amine oxidases are important enzymes, which contribute to the regulation of monoand polyamine levels. Each monomer contains one Cu(II) ion and 2,4,5-trihydroxyphenylalanine (TPQ) as cofactors.
اسدی, اسداله +2 more
core
Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy
Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie +7 more
wiley +1 more source
NADPH Oxidases and Oxidative Stress in the Pathogenesis of Atrial Fibrillation. [PDF]
Ramos-Mondragón R +5 more
europepmc +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source

