Results 161 to 170 of about 48,906 (319)
The regulation of cardiac intermediary metabolism by NADPH oxidases. [PDF]
Cardiovasc Res, 2023 Nabeebaccus AA +5 more
europepmc +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Involvement of NADPH oxidases in the Na/K‑ATPase/Src/ROS oxidant amplification loop in renal fibrosis. [PDF]
Mol Med Rep, 2023 Zhang H, Lai F, Cheng X, Wang Y.
europepmc +1 more source
Environmental Toxicology and Chemistry, EarlyView.Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff +2 more
wiley +1 more source
STIP1 drives Metabolic Reprogramming in Esophageal Squamous Cell Carcinoma via AHCY‐LDHA Axis
Exploration, EarlyView.A schematic model illustrating that LCA can inhibit ESCC growth by inhibiting the STIP1/AHCY/LDHA axis. In brief. Jin et al. demonstrated that targeting STIP1 can significantly inhibit the progression of esophageal squamous cell carcinoma. The high expression of STIP1 increased the interaction between AHCY and LDHA and then AHCY recruits PRMT3 to ...
Guoguo Jin +16 more
wiley +1 more source
Exploration, EarlyView.Long‐term migration to high‐altitude areas can readily result in chronic high‐altitude diseases; however, effective prevention and treatment methods are currently lacking. This study employed a multi‐omics approach, integrating metagenomics and metabolomics, to discover and validate that the decreased abundance of Veillonella rogosae, Streptococcus ...
Yongqiang Zhou +18 more
wiley +1 more source
NADPH oxidases in traumatic brain injury – Promising therapeutic targets?
Redox Biology, 2018 Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Despite intense investigation, no neuroprotective agents for TBI have yet translated to the clinic.
Merry W. Ma +4 more
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