The role of dual oxidases in physiology and cancer
Genetics and Molecular BiologyNOX/DUOX enzymes are transmembrane proteins that carry electrons through biological membranes generating reactive oxygen species. The NOX family is composed of seven members, which are NOX1 to NOX5 and DUOX1 and 2.
Caroline Coelho de Faria +1 more
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NOX family NADPH oxidases in mammals: Evolutionary conservation and isoform-defining sequences. [PDF]
Redox Biol, 2023 Nazari B, Jaquet V, Krause KH.
europepmc +1 more source
Local Unsupervised Learning for Image Analysis [PDF]
arXiv, 2019 Local Hebbian learning is believed to be inferior in performance to end-to-end training using a backpropagation algorithm. We question this popular belief by designing a local algorithm that can learn convolutional filters at scale on large image datasets.
arxiv
Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers [PDF]
, 1994 Martin de Boer +7 more
openalex +1 more source
Journal of Pharmacological Sciences, 2010 NADPH oxidase is a superoxide (O2−)-generating enzyme first identified in phagocytes that shows bactericidal activities. It has been reported that O2− is also produced in an NADPH-dependent manner in non-phagocytes. In the last decade, non-phagocyte-type
Masato Katsuyama
doaj
Ageing and endothelium-mediated vascular dysfunction: the role of the NADPH oxidases. [PDF]
J Physiol, 2023 Kwon OS +5 more
europepmc +1 more source
Research progress of neurovascular units involved in ischemic stroke
Ibrain, EarlyView.The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, EarlyView.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
The regulation of cardiac intermediary metabolism by NADPH oxidases. [PDF]
Cardiovasc Res, 2023 Nabeebaccus AA +5 more
europepmc +1 more source
NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets
Nature Reviews Cardiology, 2019 Yixuan Zhang +3 more
semanticscholar +1 more source