Kinetics of proton pumping in cytochrome c oxidase [PDF]
J. Chem. Phys. 130, 235105 (2009), 2008 We propose a simple model of cytochrome c oxidase, including four redox centers and four protonable sites, to study the time evolution of electrostatically coupled electron and proton transfers initiated by the injection of a single electron into the enzyme.
arxiv +1 more source
Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice [PDF]
, 2016 The major ghrelin forms, acylated ghrelin and des-acylated ghrelin, are novel gastrointestinal hormones. Moreover, emerging evidence indicates that these peptides may have other functions including neuro- and vaso-protection.
Andrews, Zane B. +8 more
core +1 more source
Mathematical Model for Chemical Reactions in Electrolyte Applied to Cytochrome $c$ Oxidase: an Electro-osmotic Approach [PDF]
arXiv, 2022 A mathematical model for chemical reactions in electrolytes is developed using an Energy variational method consistent with classical thermodynamics. Electrostatics and chemical reactions are included in properly defined energetic and dissipative functionals.
arxiv
Portosystemic hepatic encephalopathy model shows reversal learning impairment and dysfunction of neural activity in the prefrontal cortex and regions involved in motivated behavior [PDF]
Journal of Clinical Neuroscience (2011)18(5):690-4, 2011 Hepatic encephalopathy is a neurological complication that affects attention and memory. Experimental animal models have been used to study hepatic Encephalopathy, the most frequent being the portacaval shunt. In order to determine learning impairment and brain functional alterations in this model, we assessed reversal learning and neural metabolic ...
arxiv +1 more source
ROS regulation of polar growth in plant cells [PDF]
, 2016 Root hair cells and pollen tubes, like fungal hyphae, possess a typical tip or polar cell expansion with growth limited to the apical dome. Cell expansion needs to be carefully regulated to produce a correct shape and size. Polar cell growth is sustained
Denita Juárez, Silvina Paola +2 more
core +1 more source
Oxidative Medicine and Cellular Longevity, 2016 Replication of hepatitis C virus (HCV) is associated with the induction of oxidative stress, which is thought to play a major role in various liver pathologies associated with chronic hepatitis C.
O. Smirnova +6 more
semanticscholar +1 more source
NADPH Oxidases and Mitochondria in Vascular Senescence
International Journal of Molecular Sciences, 2018 Aging is the major risk factor in the development of cardiovascular diseases (CVDs), including hypertension, atherosclerosis, and myocardial infarction.
G. Salazar
semanticscholar +1 more source
Extended Linear Response for Bioanalytical Applications Using Multiple Enzymes [PDF]
Analyt. Chem. 85, 2027-2031 (2013), 2013 We develop a framework for optimizing a novel approach to extending the linear range of bioanalytical systems and biosensors by utilizing two enzymes with different kinetic responses to the input chemical as their substrate. Data for the flow-injection amperometric system devised for detection of lysine based on the function of L-Lysine-alpha-Oxidase ...
arxiv +1 more source
Novel immune mechanisms in hypertension and cardiovascular risk [PDF]
, 2017 Purpose of Review: Hypertension is a common disorder with substantial impact on public health due to highly elevated cardiovascular risk. The mechanisms still remain unclear and treatments are not sufficient to reduce risk in majority of patients ...
Guzik, Tomasz J. +3 more
core +2 more sources
NADPH oxidases differentially regulate ROS metabolism and nutrient uptake under cadmium toxicity.
Plant, Cell and Environment, 2017 The role of NADPH oxidases under cadmium (Cd) toxicity was studied using Arabidopsis thaliana mutants AtrbohC, AtrbohD and AtrbohF, which were grown under hydroponic conditions with 25 and 100 μM Cd for 1 and 5 days.
Dharmendra K. Gupta +5 more
semanticscholar +1 more source