Results 61 to 70 of about 25,108 (267)
Clarity on the Isoform-Specific Roles of NADPH Oxidases and NADPH Oxidase-4 in Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016 Atherosclerosis is a complex disease that remains a leading cause of death and disability. The formation of vascular plaques arises from the interaction of dyslipidemia with the altered function of blood vessels and immune cells. The exact cause of atherosclerosis is not known, but from the 1950s onward, oxidative modifications of lipids and proteins ...
David J R, Fulton, Scott A, Barman
openaire +2 more sources
Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction
Advanced Science, EarlyView.During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao +8 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang +8 more
wiley +1 more source
Role of NADPH Oxidase in the Endothelial Dysfunction and Oxidative Stress in Aorta of Aged Spontaneous Hypertensive Rats [PDF]
Iranian Journal of Basic Medical Sciences, 2010 Objective(s)Increased reactive oxygen species (ROS) production is implicated in the pathogenesis of arterial hypertension and the development of endothelial dysfunction.
Ashraf Taye, Sven Wind
doaj
Exogenous niacin treatment increases NADPH oxidase in kiwifruit
Brazilian Journal of Biology, 2018 Kiwifruit are a popular fruit worldwide; however, plant growth is threatened by abiotic stresses such as drought and high temperatures. Niacin treatment in plants has been shown to increase NADPH levels, thus enhancing abiotic stresses tolerance.
X. Zhu, L. Pan, T. Xiao, X. Ren, Z. Liu
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NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death.
PLoS Biology, 2021 Several studies have revealed a correlation between chronic inflammation and nicotinamide adenine dinucleotide (NAD+) metabolism, but the precise mechanism involved is unknown.
Francisco J Martínez-Morcillo +17 more
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The Importance of NADPH Oxidases and Redox Signaling in Angiogenesis
, 2017 Eukaryotic cells have to cope with the constant generation of reactive oxygen species (ROS). Although the excessive production of ROS might be deleterious for cell biology, there is a plethora of evidence showing that moderate levels of ROS are important
Angel Hernández-Hernández +1 more
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Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Journal of Pharmacological Sciences, 2010 NADPH oxidase is a superoxide (O2−)-generating enzyme first identified in phagocytes that shows bactericidal activities. It has been reported that O2− is also produced in an NADPH-dependent manner in non-phagocytes. In the last decade, non-phagocyte-type
Masato Katsuyama
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NADPH oxidases: molecular understanding finally reaching the clinical level?
, 2009 NADPH oxidases (Nox) have been the subject of very intensive research over the past several years, which has led to in-depth understanding of the function of these enzymes in health and disease. Discovery of novel Nox enzymes and identification of a very
Griendling, Kathy K. +2 more
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