Results 81 to 90 of about 48,906 (319)
Role of NADPH Oxidase in the Endothelial Dysfunction and Oxidative Stress in Aorta of Aged Spontaneous Hypertensive Rats [PDF]
Iranian Journal of Basic Medical Sciences, 2010 Objective(s)Increased reactive oxygen species (ROS) production is implicated in the pathogenesis of arterial hypertension and the development of endothelial dysfunction.
Ashraf Taye, Sven Wind
doaj
BMC Pulmonary Medicine, 2021 Objective Acute lung injury (ALI) is characterized by inflammation and oxidative stress. Nuclear factor-kappaB (NF-κB) mediates the expression of various inflammation-related genes, including the NADPH oxidase family.
Weijing Wu +8 more
doaj +1 more source
NADPH oxidases in the arbuscular mycorrhizal symbiosis [PDF]
Plant Signaling & Behavior, 2016 Plant NADPH oxidases are the major source of reactive oxygen species (ROS) that plays key roles as both signal and stressor in several plant processes, including defense responses against pathogens. ROS accumulation in root cells during arbuscular mycorrhiza (AM) development has raised the interest in understanding how ROS-mediated defense programs are
BELMONDO, SIMONE +5 more
openaire +5 more sources
Advanced Science, EarlyView.FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang +14 more
wiley +1 more source
Epigenetics and immunometabolism in diabetes and aging [PDF]
, 2018 Significance: A strong relationship between hyperglycemia, impaired insulin pathway and cardiovascular disease in type 2 diabetes (T2D) is linked to oxidative stress and inflammation.
Cosentino, Francesco, Guzik, Tomasz J.
core +2 more sources
Vascular NADPH Oxidases and Atherothrombotic Stroke
StressesOxidative stress constitutes a main molecular mechanism underlying cardiovascular diseases (CVDs). This pathological mechanism can be triggered by NADPH oxidases (NOXs), which produce reactive oxygen species (ROS).
Javier Marqués, Guillermo Zalba
doaj +1 more source
Exogenous niacin treatment increases NADPH oxidase in kiwifruit
Brazilian Journal of Biology, 2018 Kiwifruit are a popular fruit worldwide; however, plant growth is threatened by abiotic stresses such as drought and high temperatures. Niacin treatment in plants has been shown to increase NADPH levels, thus enhancing abiotic stresses tolerance.
X. Zhu, L. Pan, T. Xiao, X. Ren, Z. Liu
doaj +1 more source
Vascular Functions of NADPH Oxidases [PDF]
Hypertension, 2010 NADPH oxidases belong to a group of enzymes that generate reactive oxygen species (ROS) by electron transfer from NADPH to molecular oxygen. The product of this reaction is the superoxide anion (O2−), which undergoes secondary reactions. O2− inactivates NO to yield peroxynitrite and spontaneously or under catalysis of superoxide dismutases reacts to ...
openaire +2 more sources
VAS2870 is a pan-NADPH oxidase inhibitor [PDF]
Cellular and Molecular Life Sciences, 2012 In their detailed review ‘‘NADPH oxidases as therapeutic targets in ischemic stroke’’ [1], Kahles and Brandes discuss the pathological roles of NADPH oxidases in ischemic brain injury and the therapeutic implications. In agreement with the authors, we consider inhibition of NADPH oxidases as a promising strategy to treat ischemic stroke.
Kirstin Wingler +5 more
openaire +4 more sources
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Advanced Science, EarlyView.Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu +13 more
wiley +1 more source