Results 31 to 40 of about 5,412 (250)

Ultrastructure of Naegleria fowleri enflagellation [PDF]

open access: yesJournal of Bacteriology, 1981
Amoebae of Naegleria fowleri nN68 became elongated flagellated cells 150 to 180 min after subculture to non-nutrient buffer. N. fowleri NF69 did not become elongated or flagellated under these conditions. Electron microscopic examination of N. fowleri confirmed that it is a typical eucaryotic protist with a distinct nuclear envelope and prominent ...
S G Bradley   +3 more
openaire   +3 more sources

Naegleria fowleriin Well Water [PDF]

open access: yesEmerging Infectious Diseases, 2008
To the Editor: Naegleria fowleri, a protozoon found in hot springs and warm surface water, can cause primary amebic meningoencephalitis in humans. A survey of drinking water supply wells in Arizona determined that wells can be colonized and may be an unrecognized source of this organism that could present a human health risk. N.
Kelly R. Bright   +4 more
openaire   +3 more sources

Isolation and Identification of Naegleria Species in Irrigation Channels for Recreational Use in Mexicali Valley, Mexico

open access: yesPathogens, 2020
Members of the genus Naegleria are free-living amoebae that are widely distributed in water and soil environments. Moreover, Naegleria fowleri is a pathogenic amoeba species that causes a fatal disease in the central nervous system known as primary ...
Patricia Bonilla-Lemus   +9 more
doaj   +1 more source

Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. [PDF]

open access: yesPLoS Pathogens, 2018
Naegleria fowleri is a free-living amoeba that can also act as an opportunistic pathogen causing severe brain infection, primary amebic meningoencephalitis (PAM), in humans.
Wenxu Zhou   +7 more
doaj   +1 more source

Virtual Screening of Alkaloid and Terpenoid Inhibitors of SMT Expressed in Naegleria sp.

open access: yesMolecules, 2022
The pathogenic form of thermophilic Naegleria sp. i.e., Naegleria fowleri, also known as brain eating amoeba, causes primary amoebic encephalitis (PAM) with a >97% fatality rate.
Jason Abraham, Neha Chauhan, Supriyo Ray
doaj   +1 more source

Mannich‐Type Condensation and Domino Quinazolinone‐Amidine Rearrangement Affords Ring‐Fused Mackinazolinones with Anti‐Amoebic Activity

open access: yesAdvanced Synthesis &Catalysis, Volume 365, Issue 24, Page 4567-4575, December 19, 2023., 2023
Abstract A three‐step synthesis of anti‐amoebic, ring‐fused mackinazolinones has been developed. A Mannich‐type reaction between quinazolin‐4‐ones and N‐Cbz propanal in the presence of AgOTf afforded quinazolinones (19–94% isolated yield) bearing a newly formed heterocycle with an alkylamine appendage that, upon N‐Cbz deprotection and basification ...
Matthew S. Lish   +5 more
wiley   +1 more source

Identification of Naegleria fowleri proteins linked to primary amoebic meningoencephalitis [PDF]

open access: yes, 2017
Naegleria fowleri (N. fowleri) causes primary amoebic meningoencephalitis, a rapidly fatal disease of the central nervous system. N. fowleri can exist in cyst, flagellate or amoebic forms, depending on environmental conditions.
Cabral, Guy A   +4 more
core   +2 more sources

Water, Water Everywhere, but Every Drop Unique: Challenges in the Science to Understand the Role of Contaminants of Emerging Concern in the Management of Drinking Water Supplies

open access: yesGeoHealth, Volume 7, Issue 12, December 2023., 2023
Abstract The protection and management of water resources continues to be challenged by multiple and ongoing factors such as shifts in demographic, social, economic, and public health requirements. Physical limitations placed on access to potable supplies include natural and human‐caused factors such as aquifer depletion, aging infrastructure ...
Susan T. Glassmeyer   +10 more
wiley   +1 more source

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