Results 61 to 70 of about 129,551 (357)
Сибирский онкологический журнал, 2023 Background. Subungual squamous cell carcinoma (SCC) of thumb is a rare disease. However, it is the most common malignancy affecting the nail bed. Early recognition is crucial and important for prompt diagnosis and effective treatment.
P. Yap +4 more
doaj +1 more source
Histopathology of Nail Diseases
Journal of Investigative Dermatology, 1952 The difficulties encountered in attempting to delineate the accurate diagnosis in nail dyscrasias are well known. Where the glabrous skin is involved in a cu- taneous syndrome, the nail condition is assumed to be part of the same disorder. Practically all textbook descriptions are based on this assumption except in fungous infections where the fungi ...
White, Cleveland J., Laipply, Thomas C.
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Indian Journal of Dermatology, 2006 Background: Abnormalities of the nail unit are common in patients with connective tissue diseases. Clinical examination of the nail unit, coupled with biopsy of proximal nail fold offers an additional advantage in the diagnosis.
Nabil P +3 more
doaj
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
POS0025 COMBINED NAILFOLD CAPILLAROSCOPY AND ULTRASONOGRAPHY OF THE NAIL-ENTHESIS COMPLEX TO DISCRIMINATE PSORIATIC DISEASE FROM RHEUMATOID ARTHRITIS PATIENTS AND HEALTHY SUBJECTS [PDF]
, 2023 Giacomo Cafaro +6 more
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Anais Brasileiros de Dermatologia, 2003 A disceratose congênita é doença hereditária rara, caracterizada pela tríade de pigmentação reticulada da pele, distrofia ungueal e leucoceratose em mucosas. Alterações dentárias, gastrintestinais, geniturinárias, neurológicas, oftalmológicas, pulmonares
Sílvia Pimenta de Carvalho +4 more
doaj +1 more source
Capillaroscopy in 2016 : new perspectives in systemic sclerosis [PDF]
, 2016 Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are typical clinical aspects of SSc.
Cutolo, M +6 more
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source