Results 61 to 70 of about 9,176,233 (322)

Fingernail Configuration

open access: yesArchives of Plastic Surgery, 2015
Background A number of conditions can alter a person's fingernail configuration. The ratio between fingernail width and length (W/L) is an important aesthetic criterion, and some underlying diseases can alter the size of the fingernail.
Jin Woo Jung   +5 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Synchronous subungual glomus tumors in the same finger Tumores glômicos subungueais sincrônicos no mesmo dedo

open access: yesAnais Brasileiros de Dermatologia, 2012
The glomus tumor is an uncommon benign neoplasm of glomus cells. In the majority of the cases it is presented as a solitary painful papule in the subungual region. We report a rare case of a patient with two individual synchronous glomus tumors under the
Nilton Di Chiacchio   +3 more
doaj   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Macroscopic and dermoscopic evaluation used to differentiate subungual haemorrhage from melanocytic lesions [PDF]

open access: yesJournal of Primary Health Care, 2020
INTRODUCTIONSubungual haemorrhage describes blood located between the nail matrix and nail plate caused by trauma. Lack of recalled trauma and long duration of nail pigmentation results in specialist referrals to rule out malignant pathology.
Amanda Oakley, Mirain Phillips
doaj  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Melanoma do aparelho ungueal Nail apparatus melanoma

open access: yesAnais Brasileiros de Dermatologia, 2004
O melanoma do aparelho ungueal é apresentação relativamente rara dessa neoplasia, muitas vezes diagnosticada como nevo juncional, hematoma subungueal ou mesmo onicomicose.
Ignez Regina dos Santos Muri Mendonça   +5 more
doaj   +1 more source

Application of Transfer Learning Using Convolutional Neural Network Method for Early Detection of Terry’s Nail

open access: yesJournal of Physics: Conference Series, 2019
Nails are one part of the fingers and toes, by observing the shape and the condition of the nails, health expert can find out information about a person’s health. However, this sometimes not realized and ignored by society, even though many diseases that
M. Yani   +2 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Acrodermatitis continua of Hallopeau and psoriatic arthritis: A case report

open access: yesMedwave, 2020
A 44-year-old man, previously healthy, consulted for a three-month history of asymmetrical polyarthralgia with inflammatory features involving small and large joints.
Carolina García   +3 more
doaj   +1 more source

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