Results 151 to 160 of about 2,358 (202)
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NALORPHINE (NALLINE) ANTAGONISM TO RACEMORPHAN (DROMORAN) INTOXICATION
JAMA: The Journal of the American Medical Association, 1953Experiments with laboratory animals indicate that nalorphine (Nalline) is effective in antagonizing most of the effects of morphine, codeine, dihydromorphinone (Dilaudid), metopon, methadone, and meperidine (Demerol). Successful clinical use of nalorphine to antagonize the respiratory depression caused by morphine, dihydromorphinone, methadone, and ...
Edward F. Domino +2 more
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Pharmacological characterization of nalorphine, a kappa 3 analgesic.
The Journal of Pharmacology and Experimental Therapeutics, 1991Nalorphine is an unusual opiate. Whereas low doses of nalorphine antagonize morphine analgesia, higher nalorphine doses are analgesic, with ED50 values (95% CL) of 13.4 (11.5, 15.8) mg/kg in the writhing and 39.5 (26.6, 60.1) mg/kg in the tail-flick assay.
D, Paul +3 more
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NALORPHINE (N-ALLYLNORMORPHINE)
A.M.A. Archives of Internal Medicine, 1954HISTORY THE HISTORY of N-substituted allyl compounds of the morphine series is both fascinating and instructive. Pohl, 1 almost 40 years ago, became interested in the work of a colleague named Piazza. The latter worker had found allyl compounds to be, in general, irritating to tissues and (under some circumstances) productive of stimulant effects on ...
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Intraventricular Administration of Nalorphine to Mice implanted with Pellets of Morphine
Nature, 1966WHENEVER nalorphine is administered to white mice implanted with a pellet of morphine (base) an ‘abstinence syndrome’ is produced1. Its well-defined symptomatology and characteristics have been reported elsewhere2–4; the action of several drugs on the abstinence syndrome has also been tested5–7.
C. Maggiolo, F. Huidobro
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Antagonism of some toxic effects of dextropropoxyphene by nalorphine
Toxicology and Applied Pharmacology, 1962Abstract It has been shown that nalorphine changes the LD 50 of the intraperitoneally administered dextropropoxyphene from 68 mg/kg to 105 mg/kg. Furthermore, nalorphine antagonizes the convulsant effect of dextropropoxyphene. Also, the dextropropoxyphene-induced convulsions were of cerebral origin as evidenced by the abolition of these convulsions ...
J.E. Chapman, E.J. Walaszek
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Changes in nalorphine-induced hyperprolactinaemia after bromocriptine or sulpiride administration
European Journal of Clinical Pharmacology, 1982Nalorphine 5 mg im caused a significant increase in serum PRL in 8 healthy volunteers. Pretreatment with bromocriptine 5 mg inhibited the nalorphine-induced release of PRL, whereas sulpiride administration enhanced it.
G. Magnani +3 more
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ChemInform Abstract: NALORPHINE‐LIKE PROPERTIES OF SOME 2,3‐DIMETHYL‐3‐ARYLPIPERIDINES
Chemischer Informationsdienst, 1978AbstractAus dem Keton (I) entsteht mit Acrylnitril (II) ein Addukt (III), das zum Piperidin (IV) cyclisiert wird.
M. A. Iorio, Alan F. Casy
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NALORPHINE HYDROCHLORIDE, N.N.R. ("NALLINE HYDROCHLORIDE")
Annals of Internal Medicine, 1954Excerpt Although morphine has been one of the most important drugs in the physician's armamentarium for many years, its serious disadvantages have always been recognized.
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Some Effects of Nalorphine on the Behaviour of Healthy Human Volunteers
Journal of Mental Science, 1957Some workers have claimed that nalorphine is as potent an analgesic as morphine and does not lead to addiction.
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