Results 101 to 110 of about 96,262 (339)

Quantifying the impact of a large‐scale opioid agonist treatment program on suicide prevention in New South Wales, Australia: A data‐modeling study

open access: yesAddiction, EarlyView.
Abstract Aims This study aimed to quantify the population‐level impact of a large‐scale opioid agonist treatment (OAT) program on suicide‐related mortality among people with opioid use disorder (OUD) in New South Wales (NSW), Australia. Design This is the first study to use dynamic mathematical modeling to explore the population‐level impact of OAT on ...
Thomas James Santo Jr   +8 more
wiley   +1 more source

Naloxone distribution programs in the emergency department: A scoping review of the literature

open access: yesJournal of the American College of Emergency Physicians Open
This scoping review summarized the literature regarding naloxone distribution from emergency departments (EDs) without a prescription. Our intention was to examine various naloxone distribution programs, their methodologies, and the level of ...
Mohan K. Sindhwani   +4 more
doaj   +1 more source

Equipping Police with Naloxone Spray and Decriminalizing All Opioid Use in the U.S.: An Ethical Analysis [PDF]

open access: yes, 2018
The number of police departments carrying Narcan keeps increasing at a fast pace throughout the U.S., as it is considered an effective measure to fight the opioid epidemic. However, there have been strong oppositions to the idea of the police Narcan use.
Lee, Marvin J. H.
core  

Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain [PDF]

open access: yes, 2006
Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states.
Barrett, David   +4 more
core   +2 more sources

Medication experiences in the treatment of opioid use disorders: Insights from Reddit

open access: yesAddiction, EarlyView.
Abstract Background and Aims Better understanding the challenges faced by patients on medications for opioid use disorder (MOUD), including methadone and buprenorphine, is critical to increasing their use/retention. Social media platforms such as Reddit offer a space for patients to share their experiences with medications.
Alexandra Almeida   +5 more
wiley   +1 more source

Untrained Bystanders Administering Drone-Delivered Naloxone: An Exploratory Study

open access: yesSubstance Abuse: Research and Treatment, 2023
Introduction: Opioid overdose deaths continue to climb in the United States. Administering naloxone to an overdose victim can save their life, but rapid access to naloxone remains a barrier.
Nicole Adams   +4 more
doaj   +1 more source

Opioid modulation of GABA release in the rat inferior colliculus [PDF]

open access: yes, 2004
Background: The inferior colliculus, which receives almost all ascending and descending auditory signals, plays a crucial role in the processing of auditory information.
Casalotti, SO   +7 more
core   +3 more sources

Translational Modeling as a Tool to Evaluate the Effectiveness of Nalmefene in a Community Setting: A Critical Perspective

open access: yes
Clinical Pharmacology &Therapeutics, EarlyView.
Celine M. Laffont   +2 more
wiley   +1 more source

Naloxone dosing in the era of synthetic opioids: Applying the Goldilocks principle

open access: yesAddiction, EarlyView.
Abstract The opioid overdose epidemic remains a critical public health crisis. In recent years, synthetic opioids like fentanyl and nitazenes, have driven a sharp rise in deaths. Naloxone, an opioid receptor antagonist, has been established as a key intervention for reversing opioid overdoses and saving lives.
Mariana Gonzalez Utrilla   +8 more
wiley   +1 more source

The uptake of the pharmacy-dispensed naloxone kit program in Ontario: A population-based study.

open access: yesPLoS ONE, 2019
BACKGROUND:Naloxone is a life-saving antidote for opioid overdoses. In June 2016, the Ontario government implemented the Ontario Naloxone Program for Pharmacies (ONPP) to enhance access to naloxone.
Beatrice Choremis   +5 more
doaj   +1 more source

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