Results 41 to 50 of about 80,877 (282)

Rapid widespread distribution of intranasal naloxone for overdose prevention [PDF]

, 2017
Background: In order to have a substantial impact on overdose prevention, the expansion and scalingup of overdose prevention with naloxone distribution (OPEND) programs are needed.
Lobmaier, Philipp Paul, Clausen, Thomas, Madah-Amiri, Desiree   +2 more
core   +1 more source

If we build it, will they come? Perspectives on pharmacy-based naloxone among family and friends of people who use opioids: a mixed methods study

BMC Public Health, 2022
Background Expanding access to the opioid antagonist naloxone to reduce overdose mortality is a public health priority in the United States. Naloxone standing orders (NSOs) have been established in many states to increase naloxone dispensing at ...
Susannah Slocum, Jenny E. Ozga, Rebecca Joyce, Alexander Y. Walley, Robin A. Pollini   +4 more
doaj   +1 more source

Protocol for the Optimizing Naloxone Dispensing in Pharmacies (ONDP) Online Continuing Education Program: A Randomized Controlled Trial

Pharmacy, 2022
The number of opioid-related deaths in Canada has steadily increased since 2016 and the COVID-19 pandemic has worsened this trend. Naloxone has been pivotal for reducing opioid-related harms and death, and pharmacists play a crucial role in ensuring the ...
Ashley Cid, Alec Patten, Michael Beazely, Kelly Grindrod, Jennifer Yessis, Feng Chang   +5 more
doaj   +1 more source

Association Between State Laws Facilitating Pharmacy Distribution of Naloxone and Risk of Fatal Overdose.

JAMA Internal Medicine, 2019
Importance Given high rates of opioid-related fatal overdoses, improving naloxone access has become a priority. States have implemented different types of naloxone access laws (NALs) and there is controversy over which of these policies, if any, can curb
Rahi Abouk, R. Pacula, David Powell
semanticscholar   +1 more source

Systems analysis and improvement approach to improve naloxone distribution within syringe service programs: study protocol of a randomized controlled trial

Implementation Science, 2023
Background More than half a million Americans died of an opioid-related overdose between 1999 and 2020, the majority occurring between 2015 and 2020. The opioid overdose mortality epidemic disproportionately impacts Black, Indigenous, and people of color
Christopher F. Akiba, Sheila V. Patel, Lynn D. Wenger, Antonio Morgan-Lopez, Gary A. Zarkin, Stephen Orme, Peter J. Davidson, Alex H. Kral, Barrot H. Lambdin   +8 more
doaj   +1 more source

Method for Successfully Inducting Individuals who use Illicit Fentanyl onto Buprenorphine/naloxone

American Journal on Addictions, 2020
Background and Objectives: Individuals exposed to fentanyl are at risk of precipitated withdrawal using typical buprenorphine/naloxone induction procedures.
Denis G. Antoine, A. Huhn, E. Strain, Gavin Turner, Jasmyne Jardot, A. Hammond, K. Dunn   +6 more
semanticscholar   +1 more source

Clinical Pharmacokinetics and Pharmacodynamics of Naloxone

Clinical Pharmacokinetics
Naloxone is a World Health Organization (WHO)-listed essential medicine and is the first choice for treating the respiratory depression of opioids, also by lay-people witnessing an opioid overdose.
Teijo I. Saari, John Strang, Ola Dale
semanticscholar   +1 more source

Naloxone Availability and Cost After Transition to an Over-the-Counter Product

JAMA Health Forum
Key Points Question How did pharmacy-based access to naloxone and quoted out-of-pocket cost for naloxone change after naloxone became available as an over-the-counter (OTC) product?
G. Marley, I. Annis, Kathleen L. Egan, Paul L. Delamater, Delesha M. Carpenter   +4 more
semanticscholar   +1 more source

Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]

, 2013
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Nunez, Cristina, Edina Zelei, M Victoria Milanés, Polyák, Ágnes, Zelei, Edina, Agnes Polyák, Krisztina J Kovács, Kovács, Krisztina J., Cristina Núnez, Milanes, Victoria M., Pintér-Kübler, Bernadett, Ferenczi, Szilamér, Bernadett Pintér-Kübler, Szilamér Ferenczi   +13 more
core   +1 more source

The policy landscape for naloxone distribution in four states highly impacted by fatal opioid overdoses

Drug and Alcohol Dependence Reports, 2023
Background: Expanding access to naloxone is one of the most impactful interventions in decreasing opioid-related mortality. However, state distribution rates of naloxone are insufficient to meet community need.
Robert M. Bohler, Patricia R. Freeman, Jennifer Villani, Tim Hunt, Beth S. Linas, Alexander Y. Walley, Traci C. Green, Michelle R. Lofwall, Carly Bridden, Lisa A. Frazier, Laura C. Fanucchi, Jeffery C. Talbert, Redonna Chandler   +12 more
doaj   +1 more source