Results 21 to 30 of about 46,768 (219)

The Role of Ultra-Low-Dose Naloxone as an Additive in Anesthesia and Nerve Block: A Systematic Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims In anesthesia and analgesia, opioids alone or in combination with local anesthetics (bupivacaine, lidocaine, and ropivacaine) have been investigated to prolong peripheral nerve blocks. Ultra‐low‐dose naloxone administration in local anesthetic solutions could lengthen sensory and motor blocks through enhanced opioid effects
Mehrabanian M, Nooralishahi B, Firoozabadi MD, Sahebjam M, Ghane Y, Pishraft-Sabet H, Heidari N, Shafiee A.   +7 more
europepmc   +2 more sources

Fatal overdose prevention and experience with naloxone: A cross-sectional study from a community-based cohort of people who inject drugs in Baltimore, Maryland.

PLoS ONE, 2020
IntroductionOverdose is a leading cause of death in the United States, especially among people who inject drugs (PWID). Improving naloxone access and carrying among PWID may offset recent increases in overdose mortality associated with the influx of ...
Megan Buresh, Rachel E Gicquelais, Jacquie Astemborski, Gregory D Kirk, Shruti H Mehta, Becky L Genberg   +5 more
doaj   +1 more source

Naloxone induced pulmonary edema

, 2021
Naloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose.
Ramez Alyacoub, Carlos Remolina, Chidinma Ejikeme, Sherif Elkattawy, Muhammad Atif Masood Noori   +4 more
core   +1 more source

If we build it, will they come? Perspectives on pharmacy-based naloxone among family and friends of people who use opioids: a mixed methods study

BMC Public Health, 2022
Background Expanding access to the opioid antagonist naloxone to reduce overdose mortality is a public health priority in the United States. Naloxone standing orders (NSOs) have been established in many states to increase naloxone dispensing at ...
Susannah Slocum, Jenny E. Ozga, Rebecca Joyce, Alexander Y. Walley, Robin A. Pollini   +4 more
doaj   +1 more source

Effects of pharmacist-driven protocol on naloxone prescribing rates in two primary care clinics

Preventive Medicine Reports, 2023
The Centers for Disease Control and Prevention (CDC) Guidelines for Prescribing Opioids for Chronic Pain recommend co-prescribing naloxone as a harm reduction strategy when there is an increased risk of opioid overdose.
Ashley Daffron, Kelly Koon, Nathan P Gruenke, Sara Wettergreen   +3 more
doaj   +1 more source

Protocol for the Optimizing Naloxone Dispensing in Pharmacies (ONDP) Online Continuing Education Program: A Randomized Controlled Trial

Pharmacy, 2022
The number of opioid-related deaths in Canada has steadily increased since 2016 and the COVID-19 pandemic has worsened this trend. Naloxone has been pivotal for reducing opioid-related harms and death, and pharmacists play a crucial role in ensuring the ...
Ashley Cid, Alec Patten, Michael Beazely, Kelly Grindrod, Jennifer Yessis, Feng Chang   +5 more
doaj   +1 more source

Systems analysis and improvement approach to improve naloxone distribution within syringe service programs: study protocol of a randomized controlled trial

Implementation Science, 2023
Background More than half a million Americans died of an opioid-related overdose between 1999 and 2020, the majority occurring between 2015 and 2020. The opioid overdose mortality epidemic disproportionately impacts Black, Indigenous, and people of color
Christopher F. Akiba, Sheila V. Patel, Lynn D. Wenger, Antonio Morgan-Lopez, Gary A. Zarkin, Stephen Orme, Peter J. Davidson, Alex H. Kral, Barrot H. Lambdin   +8 more
doaj   +1 more source

Naloxone Access [PDF]

, 2022
Key Points ● Naloxone is a life-saving opioid antagonist that can reverse an opioid overdose. Tennessee law makes it available to anyone with or without a prescription and protects from civil suit any physician who prescribes it, and any bystander who ...
Kourvelas, Jeremy, Lyons, William, PhD, Tourville, Jennifer G, DNP   +2 more
core  

Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]

, 2013
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Nunez, Cristina, Edina Zelei, M Victoria Milanés, Polyák, Ágnes, Zelei, Edina, Agnes Polyák, Krisztina J Kovács, Kovács, Krisztina J., Cristina Núnez, Milanes, Victoria M., Pintér-Kübler, Bernadett, Ferenczi, Szilamér, Bernadett Pintér-Kübler, Szilamér Ferenczi   +13 more
core   +3 more sources

The policy landscape for naloxone distribution in four states highly impacted by fatal opioid overdoses

Drug and Alcohol Dependence Reports, 2023
Background: Expanding access to naloxone is one of the most impactful interventions in decreasing opioid-related mortality. However, state distribution rates of naloxone are insufficient to meet community need.
Robert M. Bohler, Patricia R. Freeman, Jennifer Villani, Tim Hunt, Beth S. Linas, Alexander Y. Walley, Traci C. Green, Michelle R. Lofwall, Carly Bridden, Lisa A. Frazier, Laura C. Fanucchi, Jeffery C. Talbert, Redonna Chandler   +12 more
doaj   +1 more source