Results 21 to 30 of about 41,379 (243)

Prehospital naloxone administration – what influences choice of dose and route of administration?

BMC Emergency Medicine, 2020
Background Amidst the ongoing opioid crisis there are debates regarding the optimal route of administration and dosages of naloxone. This applies both for lay people administration and emergency medical services, and in the development of new naloxone ...
Ida Tylleskar, Linn Gjersing, Lars Petter Bjørnsen, Anne-Cathrine Braarud, Fridtjof Heyerdahl, Ola Dale, Arne Kristian Skulberg   +6 more
doaj   +1 more source

Effects of pharmacist-driven protocol on naloxone prescribing rates in two primary care clinics

Preventive Medicine Reports, 2023
The Centers for Disease Control and Prevention (CDC) Guidelines for Prescribing Opioids for Chronic Pain recommend co-prescribing naloxone as a harm reduction strategy when there is an increased risk of opioid overdose.
Ashley Daffron, Kelly Koon, Nathan P Gruenke, Sara Wettergreen   +3 more
doaj   +1 more source

Should we be routinely co-prescribing naloxone for patients on long term opioids?

, 2021
Community naloxone supply to prevent fatal overdose needs to consider patients using pharmaceutical ...
Nielsen, Suzanne, Prathivadi, Pallavi
core   +1 more source

Fatal overdose prevention and experience with naloxone: A cross-sectional study from a community-based cohort of people who inject drugs in Baltimore, Maryland.

PLoS ONE, 2020
IntroductionOverdose is a leading cause of death in the United States, especially among people who inject drugs (PWID). Improving naloxone access and carrying among PWID may offset recent increases in overdose mortality associated with the influx of ...
Megan Buresh, Rachel E Gicquelais, Jacquie Astemborski, Gregory D Kirk, Shruti H Mehta, Becky L Genberg   +5 more
doaj   +1 more source

Systems analysis and improvement approach to improve naloxone distribution within syringe service programs: study protocol of a randomized controlled trial

Implementation Science, 2023
Background More than half a million Americans died of an opioid-related overdose between 1999 and 2020, the majority occurring between 2015 and 2020. The opioid overdose mortality epidemic disproportionately impacts Black, Indigenous, and people of color
Christopher F. Akiba, Sheila V. Patel, Lynn D. Wenger, Antonio Morgan-Lopez, Gary A. Zarkin, Stephen Orme, Peter J. Davidson, Alex H. Kral, Barrot H. Lambdin   +8 more
doaj   +1 more source

Protocol for the Optimizing Naloxone Dispensing in Pharmacies (ONDP) Online Continuing Education Program: A Randomized Controlled Trial

Pharmacy, 2022
The number of opioid-related deaths in Canada has steadily increased since 2016 and the COVID-19 pandemic has worsened this trend. Naloxone has been pivotal for reducing opioid-related harms and death, and pharmacists play a crucial role in ensuring the ...
Ashley Cid, Alec Patten, Michael Beazely, Kelly Grindrod, Jennifer Yessis, Feng Chang   +5 more
doaj   +1 more source

If we build it, will they come? Perspectives on pharmacy-based naloxone among family and friends of people who use opioids: a mixed methods study

BMC Public Health, 2022
Background Expanding access to the opioid antagonist naloxone to reduce overdose mortality is a public health priority in the United States. Naloxone standing orders (NSOs) have been established in many states to increase naloxone dispensing at ...
Susannah Slocum, Jenny E. Ozga, Rebecca Joyce, Alexander Y. Walley, Robin A. Pollini   +4 more
doaj   +1 more source

Naloxone-AuNPs@ZIF-8-Based Impedimetric Sensor Platform for Ultrasensitive Detection of Fentanyl and Fabrication of Fen-Track Prototype for Real-Field Analysis

, 2023
Opioids are considered to be a global threat, and we are facing the worst opioid crisis of the decade. Synthetic opioids like fentanyl are highly potent and deadly toward human body, and hence its detection is an inevitable requirement globally. Naloxone
Sriram Muthukumar (7511177), Anirban Paul (3489791), Ivneet Kaur Banga (17708855), Shalini Prasad (4276705)   +3 more
core   +1 more source

The policy landscape for naloxone distribution in four states highly impacted by fatal opioid overdoses

Drug and Alcohol Dependence Reports, 2023
Background: Expanding access to naloxone is one of the most impactful interventions in decreasing opioid-related mortality. However, state distribution rates of naloxone are insufficient to meet community need.
Robert M. Bohler, Patricia R. Freeman, Jennifer Villani, Tim Hunt, Beth S. Linas, Alexander Y. Walley, Traci C. Green, Michelle R. Lofwall, Carly Bridden, Lisa A. Frazier, Laura C. Fanucchi, Jeffery C. Talbert, Redonna Chandler   +12 more
doaj   +1 more source

Effect of physical exercise on pain thresholds and plasma beta-endorphins in patients with silent and symptomatic myocardial ischaemia

, 1988
In a double-blind study, eight patients with symptomatic myocardial ischaemia and nine with asymptomatic myocardial ischaemia were compared during physical exercise under naloxone (6 mg i.v.) or placebo. Plasma beta-endorphin, cortisol and catecholamines
Roskamm, H., Droste, C., Meyer-Blankenburg, H., Greenlee, Mark W.   +3 more
core   +1 more source