Heroin Adulterated with the Novel Synthetic Cannabinoid, 5F-MDMB-PINACA: A Case Series [PDF]
Introduction: Heroin can be adulterated with various substances that may or may not have pharmacological effects. Here we report a case series of 8 patients who presented to the emergency department after overdose with intravenous heroin preparation ...
Arnold, Ryan+5 more
core
Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina+6 more
core +2 more sources
The Moral Hazard of Lifesaving Innovations: Naloxone Access, Opioid Abuse, and Crime
The United States is experiencing an epidemic of opioid abuse. In response, many states have increased access to naloxone, a drug that can save lives when administered during an overdose. However, naloxone access may unintentionally increase opioid abuse
Jennifer L. Doleac, Anit Mukherjee
semanticscholar +1 more source
Medicaid managed care restrictions on medications for the treatment of opioid use disorder
Abstract Objective To examine whether Medicaid managed care plan (MCP) utilization management policies for buprenorphine–naloxone and injectable naltrexone are related to key state Medicaid program policy decisions. Data Sources and Study Setting We abstracted data on state Medicaid regulatory and policy information from publicly available sources and ...
Maureen T. Stewart+6 more
wiley +1 more source
Factors associated with gaps in naloxone knowledge: evidence from a 2022 great plains survey
Background The rising prevalence of fast-acting opioids in the USA suggests the increased need for non-professional first responder administration of naloxone.
Spencer Cooper-Ohm+3 more
doaj +1 more source
An Exploratory Study of Suboxone (Buprenorphine/ Naloxone) Film Splitting: Cutting Methods, Content Uniformity, and Stability [PDF]
Suboxone films are U.S. Food and Drug Administration approved to treat opioid dependence. While the package insert states that films should not be cut, physicians often prescribe film fractions for treatment and tapering. There is no data to support this
Conn, Kelly+6 more
core +1 more source
Addiction stigma and the production of impediments to take-home naloxone uptake
Opioid overdose deaths are a major health issue in Australia and around the world. Programmes to provide opioid consumers with ‘take-home’ naloxone to reverse overdose exist internationally, but uptake by mainstream health services and consumers remains ...
Renae Fomiatti+5 more
semanticscholar +1 more source
Patient perspectives on medications for alcohol use disorder: A systematic scoping review
Fourteen studies were included in the systematic scoping review. Important themes related to patient‐perceived barriers to medications for Alcohol Use Disorder (MAUD) were identified, including lack of awareness and misunderstanding about the effectiveness and effects of MAUD, apprehensiveness or experience with side effects, and perceived MAUD stigma.
Devin C. Tomlinson+5 more
wiley +1 more source
The rate of opioid misuse and overdose continues to increase in rural areas of the U.S. In response, access to naloxone hydrochloride (“naloxone”), an opioid antagonist used to reverse opioid overdose, has increased among both first responders and ...
Tess M. Kilwein+3 more
doaj
Summary: Background: The US overdose crisis is driven by fentanyl, heroin, and prescription opioids. One evidence-based policy response has been to broaden naloxone distribution, but how much naloxone a community would need to reduce the incidence of ...
Michael A Irvine, PhD+10 more
doaj