Results 81 to 90 of about 76,320 (330)

Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients

Drug Testing and Analysis, EarlyView.
This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke, Florian Zapf, Tanja Restin, Thomas Kraemer, Tina M. Binz   +4 more
wiley   +1 more source

Rasquache vulnerability and theories of the flesh: Working through the flesh in (auto)ethnography as a site of disruption

Feminist Anthropology, EarlyView.
Abstract In this article, I blend authoethnography and ethnography to activate a Chicanx feminist theory of the flesh, which is grounded in the sensibilities of vulnerability and rasquachismo. Rasquachismo is a politicized Mexican American visceral modality of being in the world—in art, in politics, in everydayness—that is rooted in purposeful defiance
Andrea M. Lopez
wiley   +1 more source

Biodegradable polymeric prodrugs of naltrexone [PDF]

, 1991
The development of a biodegradable polymeric drug delivery system for the narcotic antagonist naltrexone may improve patient compliance in the treatment of opiate addiction. Random copolymers consisting of the ¿-amino acids N5-(3-hydroxypropyl--glutamine
Adams, N.W., Bennet, D.B., Feijen, J., Hoes, C.J.T., Kim, S.W., Li, X.   +5 more
core   +2 more sources

Associations Between Copays, Coverage Limits for Naloxone, and Prescribing in Medicaid

Substance Abuse: Research and Treatment, 2022
Aims: To describe naloxone dispensing in Medicaid fee-for-service (FFS) and examine relationships between copays and coverage limits for naloxone and its dispensing rates.
John C Messinger, Aaron S Kesselheim, Seanna M Vine, Michael A Fischer, Rachel E Barenie   +4 more
doaj   +1 more source

Intranasal Naloxone During Recurrent Exercise in Individuals with Type‐1 Diabetes Mellitus: Evaluation of the Clinical Predictors of Pharmacokinetics and Exposure–Response

The Journal of Clinical Pharmacology, EarlyView.
Abstract Impaired awareness of hypoglycemia (IAH) impacts 25%–30% of individuals with type 1 diabetes mellitus (T1D), potentially leading to severe outcomes due to reduced symptom perception. Naloxone, a mu‐opioid receptor antagonist, shows promise as a preventive measure against IAH.
Omar N. Al Yacoub, Shen Cheng, Mohamed S. Fayed, James Fisher, Jillian Brooks, Elizabeth Seaquist, Anjali Kumar, Amir Moheet, Lynn Eberly, Lisa D. Coles   +9 more
wiley   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F, Coluzzi, Flaminia, Corcione, A., Cuomo, A, Dauri, M, Leonardi, C, Melotti, Rm, Natoli, S, Romualdi, P, Savoia, G   +9 more
core   +2 more sources

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

The Journal of Clinical Pharmacology, EarlyView.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano, Ellie He, Manjunath Shet, Glen Apseloff, Stephen C. Harris   +4 more
wiley   +1 more source

Paraventricular Nucleus Modulates Excitatory Cardiovascular Reflexes during Electroacupuncture. [PDF]

, 2016
The paraventricular nucleus (PVN) regulates sympathetic outflow and blood pressure. Somatic afferent stimulation activates neurons in the hypothalamic PVN.
Fu, Liang-Wu, Guo, Zhi-Ling, Longhurst, John C, Tjen-A-Looi, Stephanie C   +3 more
core   +1 more source

Bridging the Gap Between Knowledge and Practices Pertaining to Naloxone Use: A Single-Institution Experience in North Carolina

Journal of Patient-Centered Research and Reviews
Naloxone is a life-saving medication for opioid overdose, which claims many lives annually. This study investigated provider attitudes about, beliefs about, and barriers to naloxone use to inform an increase in provider prescription of naloxone.
Michael S. Argenyi, Gisele Bailey, Christopher J. McLouth, Erin Barnes, Candice J. McNeil   +4 more
doaj   +1 more source