Associations Between Copays, Coverage Limits for Naloxone, and Prescribing in Medicaid
Substance Abuse: Research and Treatment, 2022 Aims: To describe naloxone dispensing in Medicaid fee-for-service (FFS) and examine relationships between copays and coverage limits for naloxone and its dispensing rates.
John C Messinger +4 more
doaj +1 more source
Post‐Mortem Identification and Toxicological Findings of Fluetonitazepyne and Isotonitazepyne
Drug Testing and Analysis, EarlyView.In early 2025, five death cases in Finland tested positive for fluetonitazepyne and one for isotonitazepyne in urine drug screening. A peak corresponding to O‐dealkylated fluetonitazepyne, the 4‐OH‐nitazepyne metabolite, was present in all fluetonitazepyne‐positive urine samples and was later used in the identification of isotonitazepynein one fatal ...
Pirkko Kriikku +3 more
wiley +1 more source
Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
, 1995 Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core +1 more source
In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
, 2018 Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
core +2 more sources
Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients
Drug Testing and Analysis, EarlyView.This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke +4 more
wiley +1 more source
PLoS ONE, 2020 Rapid resuscitation of an opioid overdose with naloxone, an opioid antagonist, is critical. We developed an opioid receptor quantitative systems pharmacology (QSP) model for evaluation of naloxone dosing.
Ronald B Moss +6 more
doaj +1 more source
Paraventricular Nucleus Modulates Excitatory Cardiovascular Reflexes during Electroacupuncture. [PDF]
, 2016 The paraventricular nucleus (PVN) regulates sympathetic outflow and blood pressure. Somatic afferent stimulation activates neurons in the hypothalamic PVN.
Fu, Liang-Wu +3 more
core +1 more source
The challenge of perioperative pain management in opioid-tolerant patients [PDF]
, 2017 The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F +9 more
core +2 more sources
Hidden Costs of Ban the Box Laws: Unraveling the Effects on Drug‐Related Deaths
Health Economics, EarlyView.ABSTRACT Ban the Box (BTB) laws delay criminal background checks until the later stages of the hiring process. This study provides new evidence that BTB laws that apply to both private and public employers have negative spillover effects beyond labor market outcomes.
Oleksandra Cheipesh
wiley +1 more source
Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]
, 2019 The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R +4 more
core +1 more source