Results 81 to 90 of about 78,245 (294)
Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]
, 2012 Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas +7 more
core +2 more sources
Naloxone distribution programs in the emergency department: A scoping review of the literature
Journal of the American College of Emergency Physicians OpenThis scoping review summarized the literature regarding naloxone distribution from emergency departments (EDs) without a prescription. Our intention was to examine various naloxone distribution programs, their methodologies, and the level of ...
Mohan K. Sindhwani +4 more
doaj +1 more source
“It's such a terrible drug”: Narratives of fentanyl dealers amid the opioid overdose crisis
Criminology, EarlyView.Abstract The fentanyl‐fueled overdose crisis is historically lethal, yet the voices of those who sell fentanyl remain understudied. While research has focused extensively on people who use drugs (PWUD), the perspectives of people who sell fentanyl (PWSF) are largely absent from academic and policy discussions. This study draws on 87 in‐depth interviews
Brittney M. Schwehr, Sandra M. Bucerius
wiley +1 more source
Untrained Bystanders Administering Drone-Delivered Naloxone: An Exploratory Study
Substance Abuse: Research and Treatment, 2023 Introduction: Opioid overdose deaths continue to climb in the United States. Administering naloxone to an overdose victim can save their life, but rapid access to naloxone remains a barrier.
Nicole Adams +4 more
doaj +1 more source
Criminology, EarlyView.Abstract Discourse around drug policy presents a stark contrast between policing and harm reduction models, sparking debates on the state's regulatory versus protective role. Canada is an ideal case to study drug policy models due to its global recognition as a leader in harm reduction alongside continued reliance on policing of drugs.
Taylor Domingos
wiley +1 more source
Biodegradable polymeric prodrugs of naltrexone [PDF]
, 1991 The development of a biodegradable polymeric drug delivery system for the narcotic antagonist naltrexone may improve patient compliance in the treatment of opiate addiction. Random copolymers consisting of the ¿-amino acids N5-(3-hydroxypropyl--glutamine
Adams, N.W. +5 more
core +2 more sources
The effects of heat and freeze-thaw cycling on naloxone stability
Harm Reduction Journal, 2019 Purpose The availability of take home naloxone (THN) was increased for Canadians in 2016, including access to kits via pharmacies. Unlike typical over-the-counter (OTC) and prescription drugs, THN kits may be stored in non-standard conditions, including ...
Dulcie Lai +3 more
doaj +1 more source
Effectiveness of take ACTION online naloxone training for law enforcement officers
Health & Justice, 2023 Background Training law enforcement officers (LEOs) to administer naloxone is a recommended strategy to reduce overdose deaths in the United States. To achieve this, an evidence-based and scalable naloxone training curriculum that is easy to use and ...
Chin Hwa Dahlem +5 more
doaj +1 more source
Addiction, Volume 120, Issue 4, Page 745-755, April 2025.Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall +8 more
wiley +1 more source
Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
, 1995 Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core +1 more source