Results 91 to 100 of about 22,974 (229)

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

MedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu, Zhi‐Shan Ge, Qing‐Yue Cao, Zi‐Han Li, An Zhang, Hai‐Dong Zhu, Gao‐Jun Teng   +6 more
wiley   +1 more source

Effects of intravenous oxycodone alone or in combination with naltrexone on measures of respiratory depression: a randomized placebo-controlled study

Therapeutic Advances in Drug Safety, 2019
Background: Abuse of prescription opioids, particularly by intravenous (IV) administration, can cause respiratory depression and death. ALO-02, an abuse-deterrent opioid formulation, is designed to release sequestered naltrexone upon manipulation by ...
Almasa Bass, Lynn R. Webster, Kyle T. Matschke, Bimal K. Malhotra, Gernot Wolfram   +4 more
doaj   +1 more source

Efficacy and Safety of Pharmacological, Endoscopic, and Surgical Treatments for Obesity: A GRADE‐Based Network Meta‐Analysis

Obesity, Volume 34, Issue 2, Page 279-293, February 2026.
ABSTRACT Objective This review compared antiobesity strategies—obesity management medications (OMM), endoscopic bariatric procedures (EBP), and metabolic bariatric surgery (MBS)—with lifestyle intervention, placebo, or no therapy (LSI/Pbo/NT). Methods This network meta‐analysis included randomized clinical trials comparing OMM, EBP, and MBS versus LSI ...
Maurizio De Luca, Ricardo V. Cohen, Amanda Belluzzi, Giuseppe Navarra, Nicola Di Lorenzo, Tarissa B. Z. Petry, Paolo Sbraccia, Luca Busetto, Silvio Buscemi, Rocco Barazzoni, Benedetta Ragghianti, Edoardo Mannucci, Matteo Monami   +12 more
wiley   +1 more source

Increased activation of ErbB and NFκB signalling pathways in Darier disease affected skin

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Nancy Ernst, Ralf J. Ludwig, Artem Vorobyev   +2 more
wiley   +1 more source

Pharmacoepidemiology of Oxycodone in the USA: An Observational Study of ARCOS, Medicaid, and Medicare Drug Databases

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT The US continues to battle an opioid crisis, substantially influenced by prescription opioids, with nearly 80 000 opioid‐related deaths in 2023. This study aims to characterize oxycodone's distribution in the United States (US) from 2000 to 2023 using three data sources.
Jay P. Solgama, Apoorva Pradhan, Kenneth L. McCall, Brian J. Piper   +3 more
wiley   +1 more source

Research Progress of Exosome‐Derived microRNA in Alcohol Use Disorders: A Critical Review

Addiction Biology, Volume 31, Issue 2, February 2026.
Exosome‐derived microRNAs represent stable and mechanistically active mediators of alcohol‐induced multi‐organ injury. This review summarizes how chronic alcohol exposure reshapes exosomal miRNA cargo across the liver, immune system, and brain, highlighting key miRNAs with diagnostic value and therapeutic potential.
Bo Zhang, Ting ting Xie, Qiang Ma, Ya ping Jiang, Yu mei Wang   +4 more
wiley   +1 more source

Participants’ Treatment Perspectives on a Clinical Trial on the Use of Extended-Release Naltrexone for Substance Use Disorders: Considerations for Future Clinical Research

, 2020
Geoff Bardwell, Kaitlyn Jaffe, P. Todd Korthuis, Lindsey Richardson   +3 more
openalex   +2 more sources

Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial [PDF]

, 2019
Suchitra Krishnan‐Sarin, Stephanie S. O’Malley, Nicholas Franco, Dana A. Cavallo, Jeanette M. Tetrault, Julia Shi, Ralitza Gueorguieva, Brian Pittman, John H. Krystal   +8 more
openalex   +1 more source

GLP‐1 receptor agonists for treating obesity without diabetes: A systematic review and meta‐analysis of economic evaluations

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1339-1349, February 2026.
Abstract Aim To pool the incremental net benefits (INBs) of using glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) for treating obesity without diabetes. Materials and Methods PubMed, Embase, EconLit, CEA Registry, ProQuest Dissertation and Theses Global were searched from inception to April 2024.
Teerapon Dhippayom, Manuel Meraz, Haeseon Lee, Chin Hur, John M. Inadomi, Sajesh K. Veettil, Jeffrey D. Dunn, Nathorn Chaiyakunapruk   +7 more
wiley   +1 more source

“Convenience, Quickness, and Compassion”: Experiences of People Involved in the Criminal‐Legal System Accessing Medications for Opioid Use Disorder Services From a Mobile Unit in Chicago

Health Expectations, Volume 29, Issue 1, February 2026.
ABSTRACT Background This study aimed to explore the experiences of people diagnosed with opioid use disorder (OUD) and recently involved with the criminal‐legal system (CLS) as they received addiction treatment services from a Mobile Medications for Opioid Use Disorder (MOUD) programme in Chicago.
Toni Martinford, Dennis P. Watson, Sarah Messmer, Leyla Rashid, Monte Staton, Michael L. Dennis, Christine E. Grella, Abigail Elmes‐Patel   +7 more
wiley   +1 more source