Results 131 to 140 of about 11,695 (173)

Pharmacophore-Based QSAR Model of Multi Scaffolds as NAMPT Inhibitors & Scaffold Diversity Analysis. [PDF]

Molecules
Lee S, Zheng M, Kim K, Chun KH.
europepmc   +1 more source

NAMPT activity plays a key role in driving autoimmune processes that mediate beta-cell death and type 1 diabetes development in mice. [PDF]

Cell Death Dis
Egbase D, Sayers SR, Haq N, Gesheva VS, Varghese JJ, Bhattacharya S, Kynaston J, Hubber EL, Smith LIF, Pullen TJ, Gerdes H, Lee VK, Hopkins D, Zhao M, Cheah Y, Greally J, Butterworth S, Pearson JA, Bewick GA, Persaud SJ, Caton PW.   +20 more
europepmc   +1 more source

Activation of the impaired NAMPT/SIRT7/SOD2 axis restores alveolar progenitor cell renewal in idiopathic pulmonary fibrosis. [PDF]

J Clin Invest
Zhang X, Liu X, Qiao Y, Rabata A, Liu N, Yao C, Parimon T, Chen D, Hogaboam C, Chen P, Stripp B, Gardell SJ, Jiang D, Noble PW, Liang J.   +14 more
europepmc   +1 more source

Nicotinamide Ameliorates Deoxynivalenol-Induced Injury in Renal Cells via Inhibiting PARP1 Hyperactivation and Restoring NAD⁺ Homeostasis. [PDF]

Toxins (Basel)
Chen C, Qin Y, Luo Z, Mu P, Wen J, Deng Y.   +5 more
europepmc   +1 more source

Starving leukemia: nicotinamide phosphoribosyltransferase-dependent nicotinamide adenine dinucleotide salvage links metabolic vulnerability to therapeutic sensitivity in acute myeloid leukemia. [PDF]

Transl Cancer Res
Coelho-Silva JL, Pereira-Martins DA, Machado-Neto JA.   +2 more
europepmc   +1 more source

Hydrogen Sulfide Protects Against Cerebral Ischemia-Reperfusion Injury in Rats via S-Sulfhydrating NAMPT to Enhance Mitochondrial Function and Autophagy in Cerebrovascular Endothelial Cells. [PDF]

Pharmaceuticals (Basel)
Jiang, Liang S, Jiang Y, Jiang JR, Wang S, Yin X, Chen Z, Wen JY, Chen S.   +8 more
europepmc   +1 more source

Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer. [PDF]

Oncogene
Spellecy O, Qadir J, Han R, Zhu K, Xu B, Zhang Y, Aryal I, Lin RL, Lin AH, Faisal ASM, Napier D, Piecoro D, Scott T, Lin P, Chen L, Brewer LD, Wang C, Kyprianou N, Guo Z, Guo R, Thibault O, Yang BB, Yang XH.   +22 more
europepmc   +1 more source

Correction: Audrito et al. NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma. <i>Cancers</i> 2020, <i>12</i>, 3855. [PDF]

Cancers (Basel)
Audrito V, Messana VG, Moiso E, Vitale N, Arruga F, Brandimarte L, Gaudino F, Pellegrino E, Vaisitti T, Riganti C, Piva R, Deaglio S.   +11 more
europepmc   +1 more source

NAMPT Deficiency Promotes Endothelial-Mesenchymal Transition by Inhibiting Energy Metabolism and Lysosomal Acidification in Late-Onset Fuchs Endothelial Corneal Dystrophy. [PDF]

Invest Ophthalmol Vis Sci
Xie L, Chen M, Wu J, Li Z, Guo R, Yu H, Li X, Wang Q, Liu F, Wang J, Wang L.   +10 more
europepmc   +1 more source

Transcriptomic and experimental identification of immune- and telomere-related genes in pelvic organ prolapse. [PDF]

Front Pharmacol
Ma R, Wu J, Gong J, Pei Z, Kang J, Xu H, Yang W, Huang X, Li C.   +8 more
europepmc   +1 more source