Results 71 to 80 of about 841 (115)

Recent advances in chemical proteomics for protein profiling and targeted degradation. [PDF]

Curr Opin Chem Biol
Liu PK, Wang Z, Li L.
europepmc   +1 more source

Unlocking the therapeutic potential of HDAC8-degrading PROTACs: progress, challenges, and future directions. [PDF]

RSC Med Chem
Banerjee S, Adhikari N, Ghosh B.
europepmc   +1 more source

PROTACs in cancer immunotherapy: a minireview. [PDF]

Biochem Soc Trans
J E K, E S CA, E T C, J S G, F M F.
europepmc   +1 more source

Click. Screen. Degrade. A Miniaturized D2B Workflow for Rapid PROTAC Discovery. [PDF]

J Med Chem
Mitrović M, Greco FA, García YC, Lučić A, Hoffmann L, Chander R, Schönfeld J, Liebisch N, Sivashanmugam SA, Schwalm MP, Egner M, Lewandowski M, Merk D, Morasch V, Wolf E, Müller S, Hanke T, Proschak E, Hiesinger K, Knapp S.   +19 more
europepmc   +1 more source

PROTAC Delivery Strategies for Overcoming Physicochemical Properties and Physiological Barriers in Targeted Protein Degradation. [PDF]

Pharmaceutics
Syahputra EW, Lee H, Cho H, Park HJ, Park KS, Hwang D.   +5 more
europepmc   +1 more source

Methods to accelerate PROTAC drug discovery. [PDF]

Biochem J
Osman J, Thompson PE, Jörg M, Scanlon MJ.   +3 more
europepmc   +1 more source

Development and Evaluation of Liposomal <i>Celastrol</i>-PROTACs for Treating Triple-Negative Breast Cancer. [PDF]

Pharmaceuticals (Basel)
Li X, Yu C, Zheng G, Li Y, Cao W, Wang F.   +5 more
europepmc   +1 more source

Tumor microenvironment-targeted PROTAC nanoparticle self-assembly broadly predicted by structural descriptors. [PDF]

Sci Adv
Vogt KC, Panagiotakopoulou M, Manzari Honu MT, Perea AM, Hu X, Yu X, Raziuddin R, LaPlant Q, Ruiz S, Raju GP, Jin J, Scheinberg DA, Heller DA.   +12 more
europepmc   +1 more source

Precision-engineered PROTACs minimize off-tissue effects in cancer therapy. [PDF]

Front Mol Biosci
Shi J, Wang L, Zeng X, Xie C, Meng Z, Campbell A, Wang L, Fan H, Sun H.   +8 more
europepmc   +1 more source

Molecular engineering of lysosome-based degraders unveils a rapidly expanding therapeutic strategy. [PDF]

Autophagy
Rivault A, Dussart-Gautheret J, Benhida R, Martin AR, Auberger P, Jacquel A, Robert G.   +6 more
europepmc   +1 more source