Results 91 to 100 of about 16,460 (261)
Camelid immunoglobulins and nanobody technology [PDF]
Veterinary Immunology and Immunopathology, 2009 It is well established that all camelids have unique antibodies circulating in their blood. Unlike antibodies from other species, these special antibodies are devoid of light chains and are composed of a heavy-chain homodimer. These so-called heavy-chain antibodies (HCAbs) are expressed after a V-D-J rearrangement and require dedicated constant gamma ...
Muyldermans, S +16 more
openaire +5 more sources
Advanced Science, EarlyView.Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu +9 more
wiley +1 more source
Nanobody-Based Electrochemical Immunoassay for Sensitive Detection of Peanut Allergen Ara h 1
Peanut is widely used for food supplementation with potential allergic reactions in infants and adults, which prompted the development of reliable and accurate detection of peanut allergens with emphasis on Ara h 1.
Xuemeng Ji (9999008) +9 more
core +1 more source
Fluorescent Diarylethenes With Polar Groups: Synthesis, Spectra, and Optical Microscopy Applications
Chemistry – A European Journal, EarlyView.Blinking green and flashing red: photo‐switchable and photo‐activatable probes emitting green and red light were prepared and applied as bioconjugates in super‐resolution optical microscopy. ABSTRACT The use of photoactivatable fluorescent diarylethenes (fDAEs) in biology‐related light microscopy has been restricted by the lack of probes having freely ...
Kakishi Uno +6 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
A guide to: generation and design of nanobodies [PDF]
The FEBS Journal, 2020 A nanobody (Nb) is a registered trademark of Ablynx, referring to the single antigen‐binding domain of heavy chain‐only antibodies (HCAbs) that are circulating in Camelidae. Nbs are produced recombinantly in micro‐organisms and employed as research tools or for diagnostic and therapeutic applications.
openaire +2 more sources
Domain recognition of TcdA and TcdB nanobody clones.
, 2023 Domain recognition of TcdA and TcdB nanobody clones.
John A. Shupe (12102396) +8 more
core +1 more source
A new strategy to generate nanobodies for the coumaphos based on the synthesized nanobody libraries
Food ChemistryTo break through the bottleneck in preparation of nanobody (Nb) for chemical contaminants induced by the difficulties in the synthesis of immunogen, complexity and unexpectable efficiency of immunization, a novel strategy to generate Nbs based on the designed synthetic Nb libraries with final size up to 109 cfu/mL was adopted and succeeded in selection
Fang, Ruyu +8 more
openaire +3 more sources
The Canadian Journal of Chemical Engineering, EarlyView.Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales +6 more
wiley +1 more source
BiophysicaHuman granulocyte colony-stimulating factor (hG-CSF) is primarily used to treat neutropenia induced by cancer chemotherapy and bone marrow transplantation.
Qiang Ma +10 more
doaj +1 more source