Results 231 to 240 of about 16,460 (261)

Optogenetic Activation of Intracellular Nanobodies

2022
Intracellular antibody fragments such as nanobodies and scFvs are powerful tools for imaging and for modulating and neutralizing endogenous target proteins. Optogenetically activated intracellular antibodies (optobodies) constitute a light-inducible system to directly control intrabody activities in cells, with greater spatial and temporal resolution ...
Daseuli, Yu, Heo, Won Do
openaire   +2 more sources

Immuno-imaging using nanobodies

Current Opinion in Biotechnology, 2011
Immuno-imaging is a developing technology that aims at studying disease in patients using imaging techniques such as positron emission tomography in combination with radiolabeled immunoglobulin derived targeting probes. Nanobodies are the smallest antigen-binding antibody-fragments and show fast and specific targeting in vivo.
Vaneycken, Ilse, D'Huyvetter, Matthias, Hernot, Sophie, De Vos, Jens, Xavier, Catarina, Devoogdt, Nick, Caveliers, Vicky, Lahoutte, Tony   +7 more
openaire   +3 more sources

Nanobodies in therapeutic applications.

Current opinion in molecular therapeutics, 2007
Over the years, many antibodies have been successfully generated to treat patients with life-threatening diseases, most notably cancer. While the first generation of antibodies, originating from mice, caused severe side effects and were relatively inefficient, technological advances have made it possible to obtain fully human antibodies for therapeutic
Roovers, R.C., van Dongen, G.A., van Bergen en Henegouwen, P.M.P.   +2 more
openaire   +2 more sources

Nanobodies for NETosis Tracking and Visualization

Current Protocols
Abstract Neutrophil extracellular traps (NETs) are pivotal in the immune response, trapping and neutralizing pathogens. The process of NET formation, or NETosis, is a critical innate immune response mechanism implicated in diverse physiological and pathological processes, including infections, chronic inflammation, and cancer ...
Nicoleta Gutu, Yuli Peng, Dominik Renn, Magnus Rueping   +3 more
openaire   +2 more sources

Nanobodies made versatile

Nature Methods, 2023
openaire   +2 more sources

Nanobody: A Small Antibody with Big Implications for Tumor Therapeutic Strategy

International Journal of Nanomedicine, 2021
Ziqiang Ding, Shenxia Xie, Aiqun Liu
exaly  

Nanobody—A versatile tool for cancer diagnosis and therapeutics

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2021
Manman Liu, Duo Jin, Yangzhong Liu
exaly  

Nanobodies

RCSB Protein Data Bank, 2011
openaire   +2 more sources

Multivalent Nanobody Conjugate with Rigid, Reactive Oxygen Species Scavenging Scaffold for Multi‐Target Therapy of Alzheimer's Disease

Advanced Materials, 2023
Liyuan Zhao, Fanling Meng, Chuanzhou Li   +2 more
exaly  

Nanobodies

Scientific American, 2005
openaire   +2 more sources