Results 101 to 110 of about 1,238 (123)

Multicolored sequential resonance energy transfer for detection of simultaneous ligand binding at G protein-coupled receptors. [PDF]

Nat Commun
Valentini A, Dibnah B, Ciba M, Duncan EM, Manandhar A, Strellis B, Vita L, Lucianno O, Massey C, Coe S, Ulven T, Hudson BD, Rexen Ulven E.   +12 more
europepmc   +1 more source

Un-LOK-ing a New Approach for Conformational Selective Targeting of STK10 (LOK). [PDF]

ACS Med Chem Lett
Dettenhöfer M, Tandara LN, Amrhein JA, Kurz CG, Schwalm MP, Mensing TE, Wahl LM, Krämer A, Gerninghaus J, Lenz C, Elson L, Berger BT, Schröder M, Saxena K, Müller S, Knapp S, Greco FA, Hanke T.   +17 more
europepmc   +1 more source

Ebola virus VP35 NNLNS motif modulates viral RNA synthesis and MIB2-mediated signaling. [PDF]

Proc Natl Acad Sci U S A
Uwase G, Luthra P, Vogel OA, Batra J, La Rosa BA, Sheehan KCF, Khatavkar O, Payton JE, Davey RA, Krogan NJ, Basler CF, Leung DW, Amarasinghe GK.   +12 more
europepmc   +1 more source

Overcoming Ligand Discovery Challenges: Developing Peptide-Based Tracers for SPSB2. [PDF]

ACS Chem Biol
Lenz C, Elson L, Dopfer J, Farges F, Krämer A, Löhr F, Müller S, Guéret SM, Waldmann H, Dötsch V, Saxena K, Knapp S.   +11 more
europepmc   +1 more source

Stabilization of Native Protein-Protein Interactions with Molecular Glues: A 14-3-3 Case Study. [PDF]

Acc Chem Res
Konstantinidou M, Virta JM, Arkin MR.
europepmc   +1 more source

Biophysical Modeling Elucidates Mechanistic Principles for Rational Molecular Glue Design. [PDF]

J Chem Inf Model
Chae SJ, DeBonis J, Quinlan J, Richards R, Wang J, Gutierrez G, Tart J, Couturier M, Martinez Cuesta S, Jin M, Igoshin OA.   +10 more
europepmc   +1 more source

Identification of novel small molecule chaperone activators for neurodegenerative disease treatment.

Biomed Pharmacother
Ho AK, Jeganathan F, Bictash M, Chen HJ.
europepmc   +1 more source

A NanoBRET-based assay monitoring interactions in the USP18 signaling hub identifies the first cell-penetrant small molecule compromising USP18/ISG15 binding

Hess S, Alonso MC, Brand M, Lauw S, Lindenmann U, Göbel K, Geurink PP, Fritz G, Riedl R, Knobeloch K.   +9 more
europepmc   +1 more source

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NanoB2 to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET

Cell Reports Methods, 2023
Raimond Heukers
exaly  

Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET

Cell Chemical Biology, 2022
Angela Bridges, Joelle Goulding, Stephen J Briddon   +2 more
exaly