Polyester-Based, Biodegradable Core-Multishell Nanocarriers for the Transport of Hydrophobic Drugs [PDF]
, 2016 A water-soluble, core-multishell (CMS) nanocarrier based on a new hyperbranched polyester core building block was synthesized and characterized towards drug transport and degradation of the nanocarrier. The hydrophobic drug dexamethasone was encapsulated
Haag, Rainer +2 more
core +4 more sources
Functional Graphene Oxide Nanocarriers for Drug Delivery
International Journal of Polymer Science, 2019 The family of graphene has attracted increasing attention on account of their large specific surface area and good mechanical properties in the biomedical field.
Yuanfeng Ye +4 more
doaj +1 more source
Pharmaceutics, 2022 Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide, and its incidence is increasing. PDAC often shows resistance to several therapeutic modalities and a higher recurrence rate after surgical treatment in the early ...
Eun-Jeong Won +3 more
doaj +1 more source
In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate [PDF]
, 2019 Idebenone (IDE) is a strong antioxidant that has been proposed for the treatment of skin disorders, including skin ageing. Unfavorable physico-chemical properties make IDE a poor skin permeant where effectiveness could be improved by its loading into ...
Arena, Rosaria +8 more
core +1 more source
The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes. [PDF]
, 2015 A novel biocompatible and biodegradable drug-delivery nanoparticle (NP) has been developed to minimize the severe side effects of the poorly water-soluble anticancer drug paclitaxel (PTX) for clinical use.
Chen, R +5 more
core +2 more sources
Influence of Inner Shell Structure on the Encapsulation Behavior of Dexamethasone and Tacrolimus [PDF]
, 2017 We here present the synthesis and characterization of a set of biodegradable core–multishell (CMS) nanocarriers. The CMS nanocarrier structure consists of hyperbranched polyglycerol (hPG) as core material, a hydrophobic (12, 15, 18, 19, and 36 C-atoms ...
Fleige, Emanuel +6 more
core +1 more source
Effect of Paclitaxel Loaded Chitosan Nanoparticles and Quantum Dots on Breast Cancer
Proceedings, 2017 The aim of the study was to investigate the effect of paclitaxel loaded nanocarrier systems (chitosan nanoparticles or quantum dots) on breast cancer. Paclitaxel loaded chitosan nanoparticles and quantum dots were prepared with the particle size of 153.6
Gülen Melike Demir +5 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Drug delivery using oral route is the most popular, convenient, safest and least expensive approach. It includes oral transmucosal delivery of bioactive compounds as the mucosal cavity offers an intriguing approach for systemic drug distribution.
Bharti Mangla +5 more
doaj +1 more source
Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: Preparation, characterisation and in vitro evaluation [PDF]
, 2014 The objective of this study was to encapsulate iron in nanocarriers formulated with ascorbyl palmitate and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine polyethylene glycol (DSPE-PEG) for oral delivery.
Alexis +58 more
core +1 more source
Chitosan Based MicroRNA Nanocarriers
Pharmaceuticals, 2022 Vectorization of microRNAs has shown to be a smart approach for their potential delivery to treat many diseases (i.e., cancer, osteopathy, vascular, and infectious diseases). However, there are barriers to genetic in vivo delivery regarding stability, targeting, specificity, and internalization.
Hussein H. Genedy +2 more
openaire +4 more sources