Results 41 to 50 of about 13,099 (249)
Carbohydrate Polymer Technologies and ApplicationsDue to the increase in cancer and the necessity for effective therapies with minimum side effects, researchers throughout the world are investigating novel methods for delivering drugs to deal with this deadly disease. Nanocarriers lower side effects and
Fatemeh Mohajjel Jafari +2 more
doaj +1 more source
Structure-Based Nanocarrier Design for Protein Delivery
, 2017 Structure-based nanocarrier design for protein delivery remains challenging and has rarely been documented in the literature. We herein present a facile computer-aided approach for rational and customized design of a unique linear–dendritic telodendrimer
Juntao Luo (477073) +8 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Molecules, 2016 Bullfrog oil is a natural product extracted from the Rana catesbeiana Shaw adipose tissue and used in folk medicine for the treatment of several diseases. The aim of this study was to evaluate the extraction process of bullfrog oil, to develop a suitable
Lucas Amaral-Machado +11 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Upon contact with plasma, lipid nanoparticles (LNPs) rapidly acquire a protein corona (PC) that redefines their biological identity. In calcium‐containing environments, these coronated particles trigger the formation of a gel‐like plasma network, profoundly altering their transport properties and reducing their effective availability.
Serena Renzi +14 more
wiley +1 more source
Neural Regeneration Research, 2015 Notch pathway activation maintains neural stem cells in a proliferating state and increases nerve repair capacity. To date, studies have rarely focused on changes or damage to signal transduction pathways during cerebral hemorrhage. Here, we examined the
Wei Zou +6 more
doaj +1 more source
Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics
Pharmaceuticals, 2023 Cancer is one of the major causes of mortality, globally. Cancerous cells invade normal cells and metastasize to distant sites with the help of the lymphatic system.
Rachna M. Kumar +6 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull +11 more
wiley +1 more source
BMC BiotechnologyColorectal cancer is one of the deadliest forms of gastrointestinal cancer, with conventional treatments often facing significant limitations. As a result, new approaches, particularly in targeted drug delivery, have shown great promise.
Razie Ezati +5 more
doaj +1 more source