Results 61 to 70 of about 13,099 (249)
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Open Life Sciences, 2016 Carboxymethyl chitosan grafted with ricinoleic acid (CMC-g-RA), an amphiphilic drug carrier, was synthetized, loaded with rotenone (Rot), and characterized for particles shape, zeta potential, loading efficiency and outdoor stability.
Feng Bohua +2 more
doaj +1 more source
Transdermal Nanocarriers [PDF]
, 2010 This chapter aims to show state-of-the-art transd ermal drug-delivery nanocarriers. The advances in this field are very important at present because the skin offe rs many advantages over othe r organs due to its size. Depending on the location, we can deliver drugs very close to the target area.
openaire +1 more source
, 2015 Maxwell Korang-Yeboah,1 Yamini Gorantla,1 Simon A Paulos,1 Pankaj Sharma,2 Jaideep Chaudhary,2 Ravi Palaniappan1 1Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Mercer University, 2Center for Cancer Research and ...
Sharma P +5 more
core
Advanced Materials Interfaces, EarlyView.PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi +9 more
wiley +1 more source
Nanocarrier-based immunotherapy in cancer management and research
, 2014 Manu Smriti Singh,1 Sangeeta Bhaskar21Laboratory of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, Bonn, Germany; 2Product Development Cell, National Institute of Immunology, New Delhi, IndiaAbstract: Research in cancer immunotherapy
Singh MS, Bhaskar S
core
Efficient cytosolic access and organelle-specific targeting of polymeric nanocarriers remain unresolved challenges in nanomedicine, largely due to limited control over nano-bio interfacial interactions and intracellular trafficking pathways. Conventional
Suman Mandal (4518577) +3 more
core +1 more source
Psma-Targeted Theranostic Nanocarrier For Prostate Cancer
, 2017 Herein, we report the use of a theranostic nanocarrier (Folate-HBPE(CT20p)) to deliver a therapeutic peptide to prostate cancer tumors that express PSMA (folate hydrolase 1).
Kaittanis, Charalambos +4 more
core +1 more source
Structural and Dynamic Properties of Lipid‐Coated Gold Nanoparticles
Advanced Materials Interfaces, EarlyView.Atomistic molecular dynamics simulations reveal how lipid chemistry governs the behavior of coatings on the surface of a gold nanoparticle. Variations in headgroup charge and acyl‐chain saturation produce distinct monolayer‐like lipid organization, ranging from compact, ordered coatings to extended, dynamic shells. These findings establish a foundation
Kalpani A. Mirihana +4 more
wiley +1 more source
Development of hybrid nanocarrier library based biomaterials for cancer therapy
, 2019 Introduction: The major challenges are requested to improve the properties of nanoparticles injected systemically: i) the increase of payloads inside nanoparticles, ii) the controlled release of payloads, iii) the decrease of interaction and uptake with ...
Celia Christian +4 more
core +1 more source