Results 81 to 90 of about 51,325 (311)

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Structural characteristics, multifunctional applications, and research prospects of ferritin: a case study of sturgeon ferritin

Frontiers in Nutrition
Ferritin is a ubiquitous cage-shaped protein found in living organisms. Beyond its fundamental role in iron homeostasis, ferritin demonstrates growing application value in food engineering, nanocarrier systems, and biomedicine, owing to its unique self ...
Nida Maqsood, Zuoliang Tang, Abu Zar Ghafoor, Shuhong Li, Zhiqing Zhang, Anjun Chen, Zhiyong Zou, Man Zhou, Meiliang Li   +8 more
doaj   +1 more source

Functionalized MoS2 nanosheet-capped periodic mesoporous organosilicas as a multifunctional platform for synergistic targeted chemo-photothermal therapy [PDF]

, 2018
The combination of different therapies into a single platform has attracted increasing attention as a potential synergistic tumor treatment. Herein, the fabrication of a novel folate targeted system for chemo-photothermal therapy by using thioether ...
Bremner, David H., Li, Heyu, Niu, Shi-Wei, Wang, Haijun, Wu, Huanling, Wu, Jian-rong, Wu, Junzi, Zhu, Li-Min   +7 more
core   +2 more sources

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Characterization of particle shape, zeta potential, loading efficiency and outdoor stability for chitosan-ricinoleic acid loaded with rotenone

Open Life Sciences, 2016
Carboxymethyl chitosan grafted with ricinoleic acid (CMC-g-RA), an amphiphilic drug carrier, was synthetized, loaded with rotenone (Rot), and characterized for particles shape, zeta potential, loading efficiency and outdoor stability.
Feng Bohua, Ashraf Muhammad Aqeel, Peng Liufen   +2 more
doaj   +1 more source

Improved Anticancer Effect of Magnetite Nanocomposite Formulation of GALLIC Acid (Fe₃O₄-PEG-GA) Against Lung, Breast and Colon Cancer Cells [PDF]

, 2018
Lung cancer, breast cancer and colorectal cancer are the most prevalent fatal types of cancers globally. Gallic acid (3,4,5-trihydroxybenzoic acid) is a bioactive compound found in plants and foods, such as white tea, witch hazel and it has been reported
Dorniani, D., Fakurazi, S., Hussein, M.Z., Maniam, S., Rosman, R., Saifullah, B.   +5 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Transdermal Nanocarriers [PDF]

, 2010
This chapter aims to show state-of-the-art transd ermal drug-delivery nanocarriers. The advances in this field are very important at present because the skin offe rs many advantages over othe r organs due to its size. Depending on the location, we can deliver drugs very close to the target area.
openaire   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Graphene Oxide‐Based Gene Modulation in Preferential Elimination of Lung Cancer Cells in a 3D Tumor Microenvironment Model

Advanced NanoBiomed Research
Lung cancer remains the leading cause of cancer‐related mortality worldwide, owing to its aggressive nature, late‐stage diagnosis, and resistance to conventional therapies.
Francesca Grilli, Sadman Sakib, Fabio Variola, Shan Zou   +3 more
doaj   +1 more source