Results 71 to 80 of about 51,325 (311)

Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: Preparation, characterisation and in vitro evaluation [PDF]

, 2014
The objective of this study was to encapsulate iron in nanocarriers formulated with ascorbyl palmitate and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine polyethylene glycol (DSPE-PEG) for oral delivery.
Alexis, Ashok, Austria, Bhatia, Derek Renshaw, Derman, Ding, Fairweather-Tait, Fish, Forbes, Garcia-Fuentes, Gopinath, Guo, Gutzeit, Hallberg, Henriksen, Hermida, Hurrell, Hurrell, Hurrell, Hurrell, Janes, Kean, Knop, Kosaraju, Krishnadas, Le, Lehr, Lo Nostro, M. Gulrez Zariwala, Miralles, Moribe, Mosmann, Nedovic, Phetdee, Pizarro, Pupo, Rinaudo, Ruckmani, Sadeghi, Satyanarayana Somavarapu, Sayers, Scheers, Sebastien Farnaud, Sharma, Sharp, Stekel, Swain, Takeuchi, Thongborisute, Wegmüller, Xia, Yun, Zahra Merchant, Zariwala, Zariwala, Zaru, Zhu, Zimmermann   +58 more
core   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Synthesis and Characterization of Fe3O4/Chitosan/TiO2 Nanoparticle Novel Nanocarrier and Investigation of In Vitro Release of Vancomycin on HeLa Cancer Cell

International Journal of Biomaterials
Nanocarrier systems have gained significant attention in recent decades as an alternative to conventional drug delivery methods, which often suffer from various limitations.
Elahe Mohamadi Bian, Ayoub Moghadam
doaj   +1 more source

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Organically modified biogenic graphene oxide–mesoporous silica nanoparticles for eco-friendly and tailored release of Azadirachtin (neem) biopesticide

Chemical and Biological Technologies in Agriculture
Herein, a modified biogenic graphene oxide–mesoporous silica hybrid nanoparticle (GO–MSNs) was developed as a reliable and efficient nano-pesticide delivery system (nano-PDS) for the slow release of neem (Azadirachtin, Aza), which is known as an ...
Farzaneh Jokarshourijeh, Leila Ma′mani, Ramin Hossein, Aziz Sheikhigarjan   +3 more
doaj   +1 more source

Sialic acid accelerates the electrophoretic velocity of injured dorsal root ganglion neurons

Neural Regeneration Research, 2015
Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain.
Chen-xu Li, Guo-ying Ma, Min-fang Guo, Ying Liu   +3 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Delayed hippocampal neuronal death in young gerbil following transient global cerebral ischemia is related to higher and longer-term expression of p63 in the ischemic hippocampus

Neural Regeneration Research, 2015
The tumor suppressor p63 is one of p53 family members and plays a vital role as a regulator of neuronal apoptosis in the development of the nervous system. However, the role of p63 in mature neuronal death has not been addressed yet.
Eun Joo Bae, Bai Hui Chen, Bing Chun Yan, Bich Na Shin, Jeong Hwi Cho, In Hye Kim, Ji Hyeon Ahn, Jae Chul Lee, Hyun-Jin Tae, Seongkweon Hong, Dong Won Kim, Jun Hwi Cho, Yun Lyul Lee, Moo-Ho Won, Joon Ha Park   +14 more
doaj   +1 more source

Graphene Oxide-Gallic Acid Nanodelivery System for Cancer Therapy [PDF]

, 2016
Despite the technological advancement in the biomedical science, cancer remains a life-threatening disease. In this study, we designed an anticancer nanodelivery system using graphene oxide (GO) as nanocarrier for an active anticancer agent gallic acid ...
A Chanwitheesuk, A Lerf, AL Higginbotham, AR Maity, B Liu, B Saifullah, Bullo Saifullah, C Fu, CL Weaver, D Depan, D Dorniani, D Dorniani, D Dorniani, D Dorniani, DC Marcano, Dena Dorniani, DR Dreyer, F Barahuie, Farahnaz Barahuie, H Hu, H Zhang, H Zhang, I Mohammed-Ziegler, J An, J Liu, J Ma, J Wang, K Krishnamoorthy, KN Burger, Lance J. Twyman, M Mahkam, M Orecchioni, M Strlič, M Zhou, Mohd Zobir Bin Hussein, MS Dresselhaus, MS Dresselhaus, MY Ghotbi, N Ma, NA Ochekpe, O Akhavan, P Huang, P Shi, Palanisamy Arulselvan, R Justin, S Goenka, S Gurunathan, S Perumbilavil, S Thakur, S Verma, SH Hussein-Al-Ali, Sharida Fakurazi, SK Sahoo, T Kuila, VK Rana, WS Hummers Jr, X Huang, X Tong, Y Zhang, Y Zuo, Z Xu   +60 more
core   +1 more source